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A-level Biology - 3.1.9 Genetic Diversity may Arise by Meiosis

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Diploid cells must halve their number of chromosomes during meiosis to produce haploid gametes. This is essential because when two gametes fuse during fertilisation, the resulting zygote needs to have the correct diploid number of chromosomes.

What are the gametes in plants?

Ovum and pollen

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Key Terms

Term
Definition

What are the gametes in plants?

Ovum and pollen

Why do diploid cells (ones that divide into gametes) have to half their number of chromosomes?

Gametes have to fuse with another gamete to make a full set of genes to code for all the proteins

Explain how sexual reproduction increases genetic diversity within a species?

Fertilisation of gametes is random & produces zygotes with different combinations of chromosomes to both parents

Where does meiosis take place in?

Reproductive organs

What happens before meiosis starts?

DNA unravels and replicates, forming 2 copies of each chromosomes = called chromatids

How are sister chromatids joined?

By centromere in the middle

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TermDefinition

What are the gametes in plants?

Ovum and pollen

Why do diploid cells (ones that divide into gametes) have to half their number of chromosomes?

Gametes have to fuse with another gamete to make a full set of genes to code for all the proteins

Explain how sexual reproduction increases genetic diversity within a species?

Fertilisation of gametes is random & produces zygotes with different combinations of chromosomes to both parents

Where does meiosis take place in?

Reproductive organs

What happens before meiosis starts?

DNA unravels and replicates, forming 2 copies of each chromosomes = called chromatids

How are sister chromatids joined?

By centromere in the middle

Describe what happens in meiosis 1

Prophase 1

Chromosomes condense and super coil

Metaphase 1

Chromosomes line up along the centre of nucleus with their homologous pair (bivalents)

Anaphase 1

One of each homologous pair get pulled to either side of nucleus

Telophase 1

Nuclear envelope reforms to make 2 separate nuclei

Describe what happens in meiosis 2

Prophase 2

Chromosomes condense and super coil

Metaphase 2

Chromosomes line up along centre of nucleus still attached at centromere

Anaphase 2

Each chromatid gets pulled to either side of nucleus (centromere is divided)

Telophase 2

Nuclear envelope reforms to make 4 operate nuclei each with single copy of each chromosome

End up with 4 haploid non-identical daughter cells (n)

What is genetic variation?

Differences in the genes of individual organisms

Describe what is happening in this diagram & what this means

Crossing over

Between chromatids of homologous chromosomes

(Chromatid twist around each other & bits of chromatids swap over)

Chromatids still contain same gene but now have different combination of alleles

Name 2 ways how meiosis produces cells that are genetically different

Crossing over of chromatids

Independent segregation of chromosomes

Describe how crossing over of chromatids increases genetic variation

Each of 4 daughter cells formed from meiosis contains a different chromatid with a different set of alleles

Describe how independent segregation increases genetic variation

We don’t know which maternal or paternal chromosomes will get pulled to each side

i.e. we don’t know which chromosome (from each pair) ends up in which daughter cell

∴ 4 daughter cells produced have different combinations of those maternal and paternal chromosomes

(Leads to genetic variation in any potential offspring)

What is chromosome mutation?

When cell produced in meiosis contains variation in numbers of whole chromosomes or parts of chromosomes

(caused by errors during meiosis)

Describe and explain the appearance of this chromosome

Chromsome is formed of 2 chromatids

∵ of DNA replication

Sister chromatids are held together by centromere

What is the role of the centromere (2x)?

Holds chromatids together

Allows chromatids to be separated

This cell produces gametes by meiosis. Draw a diagram to show the chromosomes in one of the gametes.

3 chromosomes - one from each homologous pair

Crossing over of chromatids is ________

infrequent/rare

Name 3 advantages of variation (caused by meiosis) to species

Different adaptations

Passing on alleles/genes

Allows for changing environment

Explain why Plant A (has 42 chromosomes) is fertile while Plant B (has 21 chromosome) is not

Plant A’s cells are diploid - have 2 copies of each chromosome

Plant A’s chromosomes can produce haploid gametes

Plant A’s gametes receive a copy of every chromosome

Explain the role of independent segregation in meiosis

To provide genetic variation

Allows different combinations of maternal and paternal chromosomes

How do you calculate the number of different types of gametes that can be produced from a diploid cell?

Use this formula:

2n

n = number of gene pairs

Calculate the number of different types of gametes that can be produced in a species with a diploid number of 24

212 = 4096

Assuming random fertilisation, calculate the number of different combinations of maternal and paternal chromosomes in the zygotes of this species (with a diploid number of 24)

4096 x 4096 = 16 777 216

Unit 5

During meiosis, when the X and Y chromosomes pair up, they do not form a typical bivalent as do other chromosomes. Explain why. (2)

X and Y chromosomes are different sizes / shapes

Chromatids unable to line up and form bivalent / only short pairing region / most of length not homologous