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A-level Biology - 3.1.2 Cells and Cell Structure Part 4

Biology15 CardsCreated about 2 months ago

This deck covers key concepts in cell fractionation, solution conditions, and cell transport processes, as outlined in A-level Biology. It includes definitions and processes crucial for understanding cell structure and function.

Name the 3 conditions of the solution

Isotonic Ice-cold Buffered
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Key Terms

Term
Definition
Name the 3 conditions of the solution
Isotonic Ice-cold Buffered
Why does the solution have to be isotonic?
Prevents organelles damaging through osmosis
Why does the solution have to be ice-cold?
Reduces activity of enzymes that break down organelles
Why does the solution have to be buffered?
Maintain a constant pH = prevents denature of proteins/enzymes
What happens in stage 2 (filtration) of cell fractionation?
Homogenised cell solution is filtered through gauze to separate any large cell debris or tissue debris from organelles (organelles = much smaller than...
What happens in stage 3 (ultracentrifugation) of cell fractionation?
Cell fragments poured into tube & put into centrifuge - spun at low speed Heaviest organelles (nuclei) at bottom of tube = form thick sediment called ...

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TermDefinition
Name the 3 conditions of the solution
Isotonic Ice-cold Buffered
Why does the solution have to be isotonic?
Prevents organelles damaging through osmosis
Why does the solution have to be ice-cold?
Reduces activity of enzymes that break down organelles
Why does the solution have to be buffered?
Maintain a constant pH = prevents denature of proteins/enzymes
What happens in stage 2 (filtration) of cell fractionation?
Homogenised cell solution is filtered through gauze to separate any large cell debris or tissue debris from organelles (organelles = much smaller than debris)
What happens in stage 3 (ultracentrifugation) of cell fractionation?
Cell fragments poured into tube & put into centrifuge - spun at low speed Heaviest organelles (nuclei) at bottom of tube = form thick sediment called a pellet Rest of organelles stay suspended in fluid above pellet = called supernatant Supernatant is poured into another tube & spun in centrifuge at higher speed Heaviest organelles (mitochondria) form pellet at bottom Supernatant is spun at higher speed Process is repeated at higher speeds until organelles are separated out
State the order of the organelles that are separated in ultracentrifugation (from heaviest to lightest)
Nuclei to ribosomes Nuclei, chloroplast, mitochondria, lysosomes, endoplasmic reticulum, ribosomes
Golgi vesicles secrete _____
mucus
Describe how to prepare a 'temporary mount' of specimen on a slide
Pipette drop of water onto slide Use tweezers to place thin section of your specimen on top of water drop Add drop of stain - iodine dissolved in potassium iodide solution Lower cover slip using a mounted needle
Preparing a 'temporary mount' of specimen on a slide: Why do you add a stain?
∵ Highlights objects in a cell
Preparing a 'temporary mount' of specimen on a slide: When adding the cover slip, describe what you should do to avoid getting air bubbles
When adding the cover slip: Stand slip upright on slide, next to water droplet Carefully tilt and lower it so it covers the specimen
Preparing a 'temporary mount' of specimen on a slide: Why do we try avoid getting air bubbles?
∵ they obstructs your view of specimen
Mitochondria are a similar size to _____
bacteria

Define Exocytosis

Bulk transport of materials out of a cell from a vesicle

Define Endocytosis

Bulk transport of materials into a cell by the formation of vesicle from the cell membrane