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Intro to Anatomy and Physiology: Key Concepts Part 2

Anatomy and Physiology39 CardsCreated 4 months ago

This deck covers essential concepts in anatomy and physiology, focusing on cellular structures, biochemical processes, and transport mechanisms.

glycoproteins

proteins with a carbohydrate attached
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Key Terms

Term
Definition
glycoproteins
proteins with a carbohydrate attached
primary structure
linear sequence of amino acids in a protein
secondary structure
shows beta pleated sheets and alpha helices
tertiary structure
3d shape, globular or fibrous protein
quaternary structure
shown in some complex proteins; two or more proteins associate to form a final protein
acid
donates H+

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TermDefinition
glycoproteins
proteins with a carbohydrate attached
primary structure
linear sequence of amino acids in a protein
secondary structure
shows beta pleated sheets and alpha helices
tertiary structure
3d shape, globular or fibrous protein
quaternary structure
shown in some complex proteins; two or more proteins associate to form a final protein
acid
donates H+
base
donates OH-
kinetic energy
energy of motion
potential energy
energy of the position
role of enzymes
lower activation energy in chemical reactions, substrate enters active site, induced fit occurs, enzyme stresses substrate bonds, lowering activation energy and facilitating the chemical reaction to occur
plasma membrane
forms the outer limiting barrier separating the internal contents of the cell from the external environment; made up of phospholipid bilayer
nucleus
largest structure within the cell and is enclosed by a nuclear envelope. Contains genetic material, DNA, the fluid within the nucleus is called the nucleoplasm, nucleolus is dark staining body
cytoplasm
all cellular contents between the nucleus and cell membrane
cytosol
intracellular fluid, high water content
organelles
little organs- complex organized structures within cells; unique characteristic shapes and functions
diffusion
net movement of substance from where it is more concentrated to where it is less concentrated
facilitated diffusion
assists small solutes that are charged or polar into the cell past the phospholipid bilayer; occurs through channel mediated diffusion- water filled protein channels; carrier diffusion- assisted by carrier proteins
osmosis
the passive movement of water through a selectively permeable membrane; occurs to even out concentrations in and out of cell
active transport
opposes the movement of solutes by diffusion and prevents the distribution of dissolved substances from reaching equilibrium; moves a substance against a concentration gradient Ex) sodium potassium pump- ion pump concentration gradients- moves Na+ continuously out the cell and K+ into the cell; must expend ATP to do this; maintains electrochemical gradient which gives cell potential energy
isotonic
the cytosol and the solution have the same relative concentration
hypotonic
the solution has a lower concentration of solutes and there is a higher concentration of water than in the cytosol--- entry of water into the cell occurs lysis can occur
hypertonic
higher concentration of solutes and thus a lower concentration of water than in the cytosol-- water will leave the cell; crenation- cell shrinkage
secondary active transport
synport- same direction, antiport- different direction; movement of Na+ or K+ with its gradient provides enough energy to move substance in either direction
endocytosis
the cellular uptake of large substances or large amounts of substances from the external environment into the cell; used for digestion; pocket in cell membrane occurs to take in vesicle that forms on cell surface- this is called invagination
exocytosis
the means by which either large substances are secreted from the cell; macromolecules like proteins and polysaccharides are too large to be moved across the membrane even with the assistance of transport proteins; intracellular transport vesicles; vesicle fuses with plasma membrane to release contents
pinocytosis
cellular drinking; occurs when the cell internalizes droplets of interstitial fluid that contain dissolved solutes; multiple small vesicles are formed to come into the interstitial fluid; nonspecific-- all solutes in the droplet are taken into the cell
phagocytosis
cellular eating-- occurs when a cell engulfs or captures a large particle external to the cell by forming pseudopodia (false feet) to surround the particle
simple diffusion
movement of small, nonpolar particles through the plasma membrane; little energy needed
endoplasmic reticulum
extensive interconnected membrane network that varies in shape and separates fluid within the membrane structure from the cytosol; serves as a place for ribosomes to attach (Rough ER) or not (smooth ER)
golgi apparatus
modifies, packages and sorts materials that arrive from the ER in transport vesicles, forms secretory vesicles and lysosomes; made up of cisternae
vesicles
spherical shaped membrane bound sacs that transport cellular material
lysosomes
spherical shaped organelles bound by membranes that contain digestive enzymes; digest damaged organelles (autophagy); when a cell is damaged or dies, the lysosomes digest the molecular components of the cell itself-- called autolysis
mitochondria
double membrane bound organelles containing a circular strand of DNA that has genes for producing mitochondrial proteins: synthesize most ATP during aerobic cellular respiration by digestion of fuel molecules (glucose, fatty acids) in presence of oxygen; powerhouse of the cell
ribosomes
organelles composed of both ribosomal RNA and proteins; bound to a membrane or free in the cytosol; engage in protein synthesis--- bound ribosomes produce proteins that are secreted into cytosol and free ribosomes produce all other proteins
cytoskeleton
maintains cell internal structural support; made up of filaments
centrosome
amorphous region adjacent to nucleus; contains a pair of centrioles; organizes microtubules within the cytoskeleton
proteosomes
barrel shaped proteins that digest other proteins that are damaged or no longer needed; signaled by ubiquitin: use ATP
inclusions
aggregates of specific molecules-- temporary storage
peroxisomes
formed in ER or through fission-- detoxify substances through oxidation enzymes; important in liver to detoxify alcohol and other substances; work through beta oxidation-- creates CoA