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LGS A-Level OCR Biology - Unit 2 - Lipids

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The three main types of lipids are triglycerides, phospholipids, and sterols. Triglycerides act as energy stores, phospholipids form cell membranes, and sterols (like cholesterol) help regulate membrane fluidity and serve as precursors for hormones.

What are the 3 types of lipids?

Triglycerides

Phospholipids

Sterols

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Key Terms

Term
Definition

What are the 3 types of lipids?

Triglycerides

Phospholipids

Sterols

What are the 5 functions of triglycerides?

Major source of energy

Source of metabolic water

Makes up adipose tissue

provides thermal insulation under skin of animals

...

How do triglycerides compare to carbohydrates in terms of energy?

-Per g triglycerides release more energy

Being a source of metabolic water makes them useful for organisms in what kind of environment?

Desert

Give an example of an animal that uses triglycerides as thermal insulation

Killer whale in the form of blubber

When are triglycerides stored as adipose tissue?

When energy input is greater than energy output

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TermDefinition

What are the 3 types of lipids?

Triglycerides

Phospholipids

Sterols

What are the 5 functions of triglycerides?

Major source of energy

Source of metabolic water

Makes up adipose tissue

provides thermal insulation under skin of animals

Provides protection around internal organs

How do triglycerides compare to carbohydrates in terms of energy?

-Per g triglycerides release more energy

Being a source of metabolic water makes them useful for organisms in what kind of environment?

Desert

Give an example of an animal that uses triglycerides as thermal insulation

Killer whale in the form of blubber

When are triglycerides stored as adipose tissue?

When energy input is greater than energy output

Why is cholesterol transported as a lipoprotein?

They allow lipids and cholesterol to dissolve in the blood

What are the functions of sterols (2 functions)?

-Cholesterol used in cell membranes to give stability and regulate fluidity -Used to make steroid hormones

Give 2 examples of steroid hormones

Testosterone and oestrogen

Where is cholesterol manufactured?

The liver and intestines

What is the function of HDL?

-used to make cell membranes and organelle membranes -decreases membrane fluidity

Which is ‘good’ cholesterol; HDL or LDL?

HDL

What does too much LDL lead to?

-atherosclerosis (deposits in artery walls) -gall stones

How are triglycerides formed?

A condensation reaction between a glycerol molecule and 3 fatty acids

What kind of bonds are formed when a triglyceride is formed?

Ester bonds

Which part of a glycerol molecule takes part in the condensation reaction to form a triglyceride?

The hydroxyl groups

What is the structure of a glycerol molecule?

How many molecules of water are formed from the condensation reaction to form a triglyceride?

3

What does a hydrolysis reaction of a triglyceride produce?

A glycerol molecule and 3 fatty acids

i) How are phospholipids formed? ii) What kind of bonds are formed?

i) A condensation reaction between a glycerol molecule, 2 fatty acids, and a phosphate group ii) Ester bonds

What property does the head of a phospholipid have?

It is hydrophillic and polar

What property does the tail for a phosphlipid have?

It is hydrophobic and non-polar

Explain the differences between phospholipids and triglycerides

-Triglycerides contain 3 fatty acids but phospholipids only contain two and a phosphate group - Triglycerides contain 3 ester bonds but phospholipids only contain 2 - Phospholipids have a hydrophilic head

Draw a simplified version of a phospholipid

Draw a phospholipid bilayer

Explain why membranes exist as bilayers

-Both the inside and outside of cells are aqueous -therefore a single layer would repel on one side -Bilayers mean that hydrophilic heads can face into the tissue fluid and cytoplasm -with the hydrophobic tails facing away from the aqueous environments

How does cholesterol sit in phospholipid bilayers?

With the hydroxyl group in contact with the Phosphate head

What are sterols made up of?

Large alcohol molecules

As cholesterol increases membrane fluidity ____

Decreases

A decrease in cholesterol ____ fluidity

Increases

How can you test for the presence of lipids?

Add ethanol first and then the resulting mixture add to water and shake

State two roles of cholesterol in living organisms

1) Increases stability of phospholipds in cell membrane 2) Waterproofing to skin

Name two molecules that combine with cholesterol to form LDLs

1) Saturated fatty acids 2) Triglycerides/lipids