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Pharm Y2S2 - Packaging
This deck covers key concepts related to pharmaceutical packaging, including types of packaging, materials used, and potential hazards.
Define packaging.
Collection of components that surround product from manufacture until use.
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Key Terms
Term
Definition
Define packaging.
Collection of components that surround product from manufacture until use.
What is packaging necessary for?
Guaranteeing stability Delivering varied dosage forms Protection against adverse external influences Presentation of information/identification Conven...
What specific formulations require packaging enabling easy administration?
Nasal sprays Eye drops Transdermal patches Inhalers
What is the role of primary packaging?
Contains and protects the product
What is the role of secondary packaging?
Gives added physical protection, facilitates transport and contains clear/concise information
What is the role of tertiary packaging?
Used for bulk handling/shipping
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| Term | Definition |
|---|---|
Define packaging. | Collection of components that surround product from manufacture until use. |
What is packaging necessary for? | Guaranteeing stability Delivering varied dosage forms Protection against adverse external influences Presentation of information/identification Convenience |
What specific formulations require packaging enabling easy administration? | Nasal sprays Eye drops Transdermal patches Inhalers |
What is the role of primary packaging? | Contains and protects the product |
What is the role of secondary packaging? | Gives added physical protection, facilitates transport and contains clear/concise information |
What is the role of tertiary packaging? | Used for bulk handling/shipping |
What potential climatic hazards are there? | Temperature Humidity Pollutants Gases |
What potential mechanical hazards are there? | Impact Shock Compression Vibration |
What potential radiation hazards are there? | Light Solar Ionisation |
What potential spoilage hazards are there? | Biological Microbiological |
What should closures do? | Provide totally hermetic and effective microbiological seal May also be tamper resistant/evident |
What constitutes as counterfeit packaging? | Duplication Substitution Tampering |
What is the requirement of silica in glass? | 66% |
How is glass made? | Producing by heating silica, sodium carbonate and calcium carbonate |
What is type I glass? | Borosilicate Neutral and most inert type of glass, best pharmaceutical grade |
What is type II glass? | Soda lime glass Has sulphur dioxide treated surfaces to reduce leaching |
What is type III glass? | Soda lime glass produced to contain large volumes |
What is type IV glass? | NP, general purpose glass |
What colours can iron oxide glass be? | Amber Green |
What colour is cobalt oxide glass? | Blue |
What additional compounds can be added to glass? What features do they have? | Aluminium for hardness Selenium oxide for clarity Boron gives high heat shock resistance |
Give examples of thermoplastics. | Polyvinyl chloride Polyethylene |
What is the GMP approved method of plastic packaging filling? | Blow-fill-seal |
Give examples of polymers that can be used in plastic. | Nylon Acrylonitrile Polycarbon |
Which metals are highly resistant to corrosion? | Aluminium Tin Tin-coated lead |
What are laminates? | Formed by bonding together layers of different materials |
What is paper used for in packaging? | Mainly secondary packaging due to low cost, availability and ease of printing |