Sympathetic Nervous System organs innervated by cholinergic fibers?
Sweat glands and Adrenal Medulla
Key Terms
Sympathetic Nervous System organs innervated by cholinergic fibers?
Sweat glands and Adrenal Medulla
Botulinum Toxin
Prevents release of ACh at all cholinergic terminals
Nicotinic ACh receptors
Description
Location?
Ligand gated Na/K channel
Autonomic ganglia and NMJ
α1
System
Kind of receptor?
Class
Function
Sympathetic
GPCR
q
Vascular SM contraction, Pupillary dilator muscle contraction (mydriasis), Intestinal and Bladder Sphincter mu...
α2
System
Kind of receptor?
Class
Function
Sympathetic
GPCR
i
↓ sympathetic outflow, ↓ insulin release, ↓ lipolysis, ↑ platelet aggregation
β1
System
Kind of receptor?
Class
Function
Sympathetic
GPCR
s
↑ HR, contractility, rennin release, lipolysis
Related Flashcard Decks
Study Tips
- Press F to enter focus mode for distraction-free studying
- Review cards regularly to improve retention
- Try to recall the answer before flipping the card
- Share this deck with friends to study together
| Term | Definition |
|---|---|
Sympathetic Nervous System organs innervated by cholinergic fibers? | Sweat glands and Adrenal Medulla |
Botulinum Toxin | Prevents release of ACh at all cholinergic terminals |
Nicotinic ACh receptors Description Location? | Ligand gated Na/K channel Autonomic ganglia and NMJ |
α1 System Kind of receptor? Class Function | Sympathetic GPCR q Vascular SM contraction, Pupillary dilator muscle contraction (mydriasis), Intestinal and Bladder Sphincter muscle contraction |
α2 System Kind of receptor? Class Function | Sympathetic GPCR i ↓ sympathetic outflow, ↓ insulin release, ↓ lipolysis, ↑ platelet aggregation |
β1 System Kind of receptor? Class Function | Sympathetic GPCR s ↑ HR, contractility, rennin release, lipolysis |
β2 System Kind of receptor? Class Function | Sympathetic GPCR s Vasodilation, Bronchodilation, ↓ Uterine Tone (tocolysis) ↑ HR, contractility, lipolysis, insulin release Ciliary Muscle Relaxation and ↑ Aqueous Humor production |
M1 System Kind of receptor? Class Function | Parasympathetic GPCR q CNS, Enteric Nervous System |
M2 System Kind of receptor? Class Function | Parasympathetic GPCR i ↓ HR and atrai contractility |
M3 System Kind of receptor? Class Function | Parasympathetic q GPCR Exocrine gland secretion, gut peristalsis, bladder contraction, Bronchoconstriction, Pupillary sphincter muscle contraction (Miosis), Ciliary muscle contraction (accommodation) |
D1 Kind of receptor? Class Function | GPCR s Relaxes renal vascular smooth muscle |
D2 Kind of receptor? Class Function | GPCR i Modulates transmitter release, esp in brain |
H1 Kind of receptor? Class Function | GPCR q Nasal and Bronchial mucus production, contraction of bronchioles, pruritus, pain |
H2 Kind of receptor? Class Function | GPCR s Gastric Acid Secretion |
V1 Kind of receptor Class Function | GPCR q Vascular smooth muscle contraction |
V2 Kind of receptor Class Function | GPCR s ↑ water permeability and reabsorption in collecting tubule of kidneys |
Autonomic Receptor Mnemonic | QISS and QIQ until you're SIQ of SQS α1, α2, β1, β2 M1, M2, M3 D1, D2 H1, H2 V1, V2 |
Autonomic drugs that use IP3/DAG | “HAVe 1 M&M” H1, α1, V1, M1, M3 |
Autonomic drugs that ↓ cAMP | “MAD2” M2, α2, D2 |
Autonomic drugs that ↑ cAMP | Gs “Bill Bob Doesn’t Have Value” β1, β2, D1, H2, V2 |
Hemicholinium | Blocks re-uptake of choline at ACh nerve terminal |
Vesamicol | Blocks ACh packaging into vesicles |
Metyrosine | Inhibits conversion of Tyrosine to DOPA |
Reserpine | Inhibits packaging of DA into vesicles May be turned into NE in vesicle |
Guanethidine | Inhibits release of NE |