QQuestionAnatomy and Physiology
QuestionAnatomy and Physiology
A single nucleotide deletion during DNA replication:
A. causes one amino acid of the protein to be incorrect
B. causes all of the amino acids of the protein to be incorrect
C. causes the amino acids encoded by nucleotides after the deletion to be incorrect
D. causes the amino acids encoded by nucleotides before the deletion to be incorrect
E. has no effect on the resulting protein
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Answer
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Step 1: Understand the concept of a single nucleotide deletion during DNA replication.
A single nucleotide deletion means that one nucleotide is missing in the DNA sequence. This error will cause a frameshift, leading to an entirely different sequence of amino acids being produced during protein synthesis.
Step 2: Analyze the options given in the question.
Option A: Causes one amino acid of the protein to be incorrect. This is not the case, as a single nucleotide deletion results in a frameshift, causing multiple amino acids to be incorrect. Option B: Causes all of the amino acids of the protein to be incorrect. This is correct, as a single nucleotide deletion results in a frameshift, causing multiple amino acids to be incorrect. Option C: Causes the amino acids encoded by nucleotides after the deletion to be incorrect. This is true, but it is not the only effect, as the deletion causes a frameshift affecting all subsequent amino acids. Option D: Causes the amino acids encoded by nucleotides before the deletion to be incorrect. This is not true, as the deletion only affects the reading frame starting at the point of the deletion and does not affect the sequence before the deletion. Option E: Has no effect on the resulting protein. This is incorrect, as a single nucleotide deletion has a significant impact on the resulting protein.
Final Answer
The correct answer is option B: causes all of the amino acids of the protein to be incorrect.
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