### **Where are ribosomes made?**

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: Ribosomes are made in the nucleolus, which is a substructure within the nucleus of eukaryotic cells. : The process of ribosome assembly begins in the nucleolus with the transcription of ribosomal DNA (rDNA) genes by RNA polymerase I to produce the initial rRNA transcript. : The rRNA transcript is cleaved and modified to form the mature rRNAs. : The assembled rRNAs and ribosomal proteins form small and large ribosomal subunits. : Once the small and large ribosomal subunits are formed, they are exported from the nucleolus to the cytoplasm, where they can participate in protein synthesis. The nucleolus is the site of ribosome biogenesis, where ribosomal RNA (rRNA) and ribosomal proteins are assembled to create ribosomal subunits, which are then exported to the cytoplasm for protein synthesis.

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QuestionAnatomy and Physiology

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Step 1
: Ribosomes are made in the nucleolus, which is a substructure within the nucleus of eukaryotic cells.

Step 2
: The process of ribosome assembly begins in the nucleolus with the transcription of ribosomal DNA (rDNA) genes by RNA polymerase I to produce the initial rRNA transcript.

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