2024-2025 Thyroid Disorders (PEARLS) (Smarty PANCE) with Answers (65 Solved Questions)
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Thyroid Disorders
(PEARLS) (Smarty PANCE)
100% VERIFIED ANSWERS
2024/2025 CORRECT
↑ PTH and ↑ CA+
Hyperparathyroidism
↓ PTH and ↓ CA+
Hypoparathyroidism
A 62-year-old woman presents complaining of joint pain, polyuria, polydipsia, and
generalized fatigue. The woman reports a history of recurrent kidney stones and
depression. Radiographs show osteopenia and subperiosteal resorption on the
phalanges.
Hyperparathyroidism
Tingling, tetany, trousseau's
Hypoparathyroidism
↓ TSH and ↑ Free T4
Hyperthyroidism
Weight gain, fatigue, edema
Hypothyroidism
(PEARLS) (Smarty PANCE)
100% VERIFIED ANSWERS
2024/2025 CORRECT
↑ PTH and ↑ CA+
Hyperparathyroidism
↓ PTH and ↓ CA+
Hypoparathyroidism
A 62-year-old woman presents complaining of joint pain, polyuria, polydipsia, and
generalized fatigue. The woman reports a history of recurrent kidney stones and
depression. Radiographs show osteopenia and subperiosteal resorption on the
phalanges.
Hyperparathyroidism
Tingling, tetany, trousseau's
Hypoparathyroidism
↓ TSH and ↑ Free T4
Hyperthyroidism
Weight gain, fatigue, edema
Hypothyroidism
↑ TSH and ↓ Free T4
Hypothyroidism
Weight loss, anxiety, tachycardia
Hyperthyroidism
Hoarse voice, cold nodule on thyroid uptake scan
Thyroid neoplastic disease
Neck tenderness preceded by a viral illness (will likely be a URI) a few weeks
earlier.
Thyroiditis
↑ PTH usually caused by a PTH secreting parathyroid ADENOMA
Primary hyperparathyroidism
Secondary hyperparathyroidism - Chronic kidney disease is the most common
cause of secondary hyperparathyroidism.
↑ PTH by a physiologic response to hypocalcemia or vitamin D deficiency.
Thyroid nodules larger than _____ cm should be biopsied?
Lesions larger than 1 cm should be biopsied. Lesions with features suggestive of
malignancy (Microcalcifications, hypoechogenicity, a solid nodule, irregular nodule
margins, chaotic intranodular vasculature, and a nodule that is more tall than wide) and
those in patients with risk factors for thyroid cancer should be biopsied, regardless of
size. Smaller lesions and those with benign histology can be followed and reevaluated if
they grow.
Initial hyperthyroidism which may occur with Hashimoto's thyroiditis?
Hypothyroidism
Weight loss, anxiety, tachycardia
Hyperthyroidism
Hoarse voice, cold nodule on thyroid uptake scan
Thyroid neoplastic disease
Neck tenderness preceded by a viral illness (will likely be a URI) a few weeks
earlier.
Thyroiditis
↑ PTH usually caused by a PTH secreting parathyroid ADENOMA
Primary hyperparathyroidism
Secondary hyperparathyroidism - Chronic kidney disease is the most common
cause of secondary hyperparathyroidism.
↑ PTH by a physiologic response to hypocalcemia or vitamin D deficiency.
Thyroid nodules larger than _____ cm should be biopsied?
Lesions larger than 1 cm should be biopsied. Lesions with features suggestive of
malignancy (Microcalcifications, hypoechogenicity, a solid nodule, irregular nodule
margins, chaotic intranodular vasculature, and a nodule that is more tall than wide) and
those in patients with risk factors for thyroid cancer should be biopsied, regardless of
size. Smaller lesions and those with benign histology can be followed and reevaluated if
they grow.
Initial hyperthyroidism which may occur with Hashimoto's thyroiditis?
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