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Audits and Inspections of Clinical Trials

Auditing5 CardsCreated 3 months ago

This deck covers key concepts related to audits and inspections in clinical trials, focusing on definitions and goals as outlined by regulatory authorities.

According to ICH E6, an inspection is defined as:

An inspection is defined as the act by a regulatory authority of conducting an official review of documents, facilities, records, and any other resources related to a clinical trial. A systematic and independent examination of trial-related activities and documents is 'an audit' and the act of overseeing the progress of a clinical trial is 'monitoring.'
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Key Terms

Term
Definition
According to ICH E6, an inspection is defined as:
An inspection is defined as the act by a regulatory authority of conducting an official review of documents, facilities, records, and any other resour...
When the FDA conducts an inspection, the inspectors will:
Review regulatory records.
The overall goal of monitoring, audits, and inspection activities is to:
Ensure the protection of human research subjects and data integrity.
According to ICH E6, an 'audit' is defined as:
A systematic and independent examination of trial-related activities and documents.
OHRP is an oversight body primarily concerned with:
Protection of human research subjects

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TermDefinition
According to ICH E6, an inspection is defined as:
An inspection is defined as the act by a regulatory authority of conducting an official review of documents, facilities, records, and any other resources related to a clinical trial. A systematic and independent examination of trial-related activities and documents is 'an audit' and the act of overseeing the progress of a clinical trial is 'monitoring.'
When the FDA conducts an inspection, the inspectors will:
Review regulatory records.
The overall goal of monitoring, audits, and inspection activities is to:
Ensure the protection of human research subjects and data integrity.
According to ICH E6, an 'audit' is defined as:
A systematic and independent examination of trial-related activities and documents.
OHRP is an oversight body primarily concerned with:
Protection of human research subjects