StudyXY
RegisterLog in
Pharmacology /DENH 620 Pharmacology: Chapter 6 Opiod (Narcotic) Analgesics and Antagonists

DENH 620 Pharmacology: Chapter 6 Opiod (Narcotic) Analgesics and Antagonists

Pharmacology19 CardsCreated 2 months ago

This deck covers key concepts from Chapter 6 of DENH 620 Pharmacology, focusing on opioid (narcotic) analgesics and antagonists. It includes definitions, drug classifications, and the physiological effects of opioids.

PrintEmbedImportReport

What are the 3 opioid receptors?

mu (µ), kappa (k), delta (∂)
Tap or swipe ↕ to flip
Swipe ←→Navigate
SSpeak
FFocus
1/19

Key Terms

Term
Definition
What are the 3 opioid receptors?
mu (µ), kappa (k), delta (∂)
What do opioids function to do?
alter the reception of reaction to pain
mu (µ) receptors produce?
analgesia (the inability to feel pain)
k receptors produce?
analgesia and dysphoria with pentazocine (uneasiness or dissatisfaction)
What is ADME?
The components of how a drug is handled/processed by a living organism: Absorption, Distribution, Metabolism, Excretion
Absorption
the absorption of a drug by lungs, nasal, and oral mucosa through the mucous membrane and intact skin
Log in to view all terms

Related Flashcard Decks

Pharmacology

My EPPP Practice Questions: Physio and Psychopharm Big 6

This flashcard set covers key topics in Physiological Psychology and Psychopharmacology for the EPPP. It explains dysprosody, a speech disorder affecting rhythm and intonation, often seen in Broca’s and other nonfluent aphasias following brain injury.

22 cards
View Deck
Pharmacology

Psychotherapy: 99b - Antipsychotics

This flashcard set covers key pharmacological aspects of antipsychotic medications. First-generation (typical) antipsychotics primarily work via D2 dopamine receptor blockade in the mesolimbic pathway. High-potency agents (e.g., haloperidol) cause more extrapyramidal symptoms, while low-potency agents (e.g., chlorpromazine) have more anticholinergic and antihistamine side effects. Among atypicals, ziprasidone, aripiprazole, and lurasidone are associated with the least metabolic disruption.

15 cards
View Deck
Pharmacology

Psychotherapy: SAS/Review

This flashcard set covers important clinical insights related to pharmacology, defense mechanisms, neurodegenerative disorders, and long-term medication side effects. Topics include serotonin-related risks with opioids like tramadol and fentanyl, the use of sublimation as a defense mechanism, early cognitive decline in Lewy Body Dementia, and the emergence of tardive dyskinesia after prolonged use of first-generation antipsychotics.

54 cards
View Deck
Pharmacology

Psychopharmacology

This content distinguishes olanzapine as an atypical (second-generation) antipsychotic known for fewer extrapyramidal side effects but notable metabolic risks. It also identifies venlafaxine as a serotonin and noradrenaline reuptake inhibitor (SNRI), a class of antidepressants used often as second-line treatment for depression.

9 cards
View Deck
Pharmacology

Psychopharmacology: Psychosexual

This content outlines erectile dysfunction as a common consequence of performance anxiety in a young man with no prior sexual experience. It also identifies citalopram, a selective serotonin reuptake inhibitor (SSRI), as a frequent cause of orgasmic dysfunction due to its known side effects of delayed ejaculation and anorgasmia.

10 cards
View Deck
Pharmacology

USMLE - Pharm Part 1

Describes the relationship between enzyme velocity (v) and substrate concentration ([S]) using the equation v = (Vmax[S])/(Km + [S]). Vmax reflects enzyme capacity, while Km indicates substrate affinity (lower Km = higher affinity). The graph is hyperbolic in shape.

100 cards
View Deck

Study Tips

  • Press F to enter focus mode for distraction-free studying
  • Review cards regularly to improve retention
  • Try to recall the answer before flipping the card
  • Share this deck with friends to study together
DENH 620 Pharmacology: Chapter 6 Opiod (Narcotic) Analgesics and Antagonists
TermDefinition
What are the 3 opioid receptors?
mu (µ), kappa (k), delta (∂)
What do opioids function to do?
alter the reception of reaction to pain
mu (µ) receptors produce?
analgesia (the inability to feel pain)
k receptors produce?
analgesia and dysphoria with pentazocine (uneasiness or dissatisfaction)
What is ADME?
The components of how a drug is handled/processed by a living organism: Absorption, Distribution, Metabolism, Excretion
Absorption
the absorption of a drug by lungs, nasal, and oral mucosa through the mucous membrane and intact skin
Distribution
where drug undergoes variable first pass metabolism in the liver or intestinal wall, thus reducing their bioavailability
Metabolism
occurs in the liver in conjugation with glucuronic acid
Excretion
where metabolized opioids are excreted by glomerular filtration and then excreted by urine
What does first pass metabolism do?
reduces bioavailability of a certain opioid/drug (distribution phase)
____ is the opioid analgesic by which other opioids are measured?
Morphine
What class of drug is Morphine, Oxycodone, Hydrocodone?
Class II
What class of drug is Tylenol 3?
Class III
What is the Controlled Substance Act of 1970?
an Act that sets requirements for writing prescriptions for drugs (that are often prescribed in the dental office)
Schedule II drugs ____ be refilled?
Cannot
What is opioid addiction?
A disease of the brain that involves both a physical dependence and a psychologic dependence on the drug
What are the two major signs of opioid addiction?
Cravings/Intense desire for the drug, Loss of control of the ability to stop using the drug or to control the amount
The most common side effect of the opioid analgesics?
Sedation
Long term administration of opioid analgesics can lead to?
Tolerance, Habituation, Dependence