Pharm Y2S2 - Astra Zeneca

My EPPP Practice Questions: Physio and Psychopharm Big 6

This flashcard set covers key topics in Physiological Psychology and Psychopharmacology for the EPPP. It explains dysprosody, a speech disorder affecting rhythm and intonation, often seen in Broca’s and other nonfluent aphasias following brain injury.

Psychotherapy: 99b - Antipsychotics

This flashcard set covers key pharmacological aspects of antipsychotic medications. First-generation (typical) antipsychotics primarily work via D2 dopamine receptor blockade in the mesolimbic pathway. High-potency agents (e.g., haloperidol) cause more extrapyramidal symptoms, while low-potency agents (e.g., chlorpromazine) have more anticholinergic and antihistamine side effects. Among atypicals, ziprasidone, aripiprazole, and lurasidone are associated with the least metabolic disruption.

Psychotherapy: SAS/Review

This flashcard set covers important clinical insights related to pharmacology, defense mechanisms, neurodegenerative disorders, and long-term medication side effects. Topics include serotonin-related risks with opioids like tramadol and fentanyl, the use of sublimation as a defense mechanism, early cognitive decline in Lewy Body Dementia, and the emergence of tardive dyskinesia after prolonged use of first-generation antipsychotics.

Psychopharmacology

This content distinguishes olanzapine as an atypical (second-generation) antipsychotic known for fewer extrapyramidal side effects but notable metabolic risks. It also identifies venlafaxine as a serotonin and noradrenaline reuptake inhibitor (SNRI), a class of antidepressants used often as second-line treatment for depression.

Psychopharmacology: Psychosexual

This content outlines erectile dysfunction as a common consequence of performance anxiety in a young man with no prior sexual experience. It also identifies citalopram, a selective serotonin reuptake inhibitor (SSRI), as a frequent cause of orgasmic dysfunction due to its known side effects of delayed ejaculation and anorgasmia.

USMLE - Pharm Part 1

Describes the relationship between enzyme velocity (v) and substrate concentration ([S]) using the equation v = (Vmax[S])/(Km + [S]). Vmax reflects enzyme capacity, while Km indicates substrate affinity (lower Km = higher affinity). The graph is hyperbolic in shape.