Biology /Pharm Y2S2 - Streptococcus Pyogenes
Describe the microbiology of strep pyogenes.
gram positive cocci arranged in chains group A streptococcus facultative
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Term
Definition
Describe the microbiology of strep pyogenes.
gram positive cocci arranged in chains group A streptococcus facultative
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What are the virulence factors of strep p?
bacterial capsule exotoxin production (e.g. Streptolyisn S) and immune evasion dissemination
What are the common strep p infections?
sore throat cellulitis scarlet fever meningitis pneumonia
What are the differential diagnoses of strep throat?
Glandular fever: viral infection Cancer: persistent sore throat Quinsy: painful collection of pus Epiglotittis: inflammation of epiglottis
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What are the danger symptoms of sore throat?
persistent high temp symptoms for longer that 4-5 days difficulty swallowing or breathing
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What is the treatment for strep throat?
OTC analgesics and antibiotics Carbimazole DMARDS
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| Term | Definition |
|---|---|
Describe the microbiology of strep pyogenes. | gram positive cocci arranged in chains group A streptococcus facultative |
What are the virulence factors of strep p? | bacterial capsule exotoxin production (e.g. Streptolyisn S) and immune evasion dissemination |
What are the common strep p infections? | sore throat cellulitis scarlet fever meningitis pneumonia |
What are the differential diagnoses of strep throat? | Glandular fever: viral infection Cancer: persistent sore throat Quinsy: painful collection of pus Epiglotittis: inflammation of epiglottis |
What are the danger symptoms of sore throat? | persistent high temp symptoms for longer that 4-5 days difficulty swallowing or breathing |
What is the treatment for strep throat? | OTC analgesics and antibiotics Carbimazole DMARDS |
What are the complications of Group A Strep infections? | acute rheumatic fever rheumatic heart disease post streptococcal glomerulephritis bacteraemia / septicaemia necrotising fasciitis TSS |
What are the risk factors for cellulitis? | obese weakened immune system poorly controlled diabetes / circulation problems chickenpox or shingles lymphoeddema IV drug use previous episodes of cellulitis |
What are the endogenous carriers of Gp A streptococci? | interdigital toe spaces vagina anus |
What are the differential diagnosis for cellulitis? | eczema lymphoedema allergic reaction |
What is the treatment for mild/moderate cellulitis infections? | 7-14 days antibiotics at home - Phenoxymethylpenicllin (clarithromycin / clindamycin) |
What is the treatment for advanced cellulitis infection? | IV benzylpenicillin (vancomycin) |
What are the potential complications of cellulitis? | bacteraemia / septicaemia necrotising fasciitis abscess facial cellulitis meningitis |