2024-2025 Anemias Disorders (PEARLS) (Smarty PANCE) with Answers (73 Solved Questions)
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Anemias (PEARLS) - Smarty
PANCE 100% VERIFIED
ANSWERS 2024/2025
Normal or ↓ MCV, ↓ TIBC, ↑ Ferritin (high iron stores) ↓ serum erythropoietin
Anemia of chronic disease
The only anemia where all three cell lines are decreased (pancytopenia) ↓ WBC, ↓
RBC, ↓ Platelets - will have normal MCV and ↓ Retic
Aplastic anemia
↓ Folate, ↑ MCV (macrocytic anemia) looks like B12 but no neurologic symptoms.
Common in alcoholics
Folate deficiency
After infection or medication in an African American male + Heinz Bodies and Bite
Cells on smear. Flare triggers: Fava beans, antimalarials, sulfonamides
G6PD deficiency
History of jaundice, transfusion, new medication or infection (+) direct coombs
test
Autoimmune Hemolytic anemia
↓ MCV (microcytic), ↑ TIBC, ↓ Ferritin (low iron stores) ↓ MCH (hypochromic).
Associated with pica and nail spooning, target cells
Iron deficiency
PANCE 100% VERIFIED
ANSWERS 2024/2025
Normal or ↓ MCV, ↓ TIBC, ↑ Ferritin (high iron stores) ↓ serum erythropoietin
Anemia of chronic disease
The only anemia where all three cell lines are decreased (pancytopenia) ↓ WBC, ↓
RBC, ↓ Platelets - will have normal MCV and ↓ Retic
Aplastic anemia
↓ Folate, ↑ MCV (macrocytic anemia) looks like B12 but no neurologic symptoms.
Common in alcoholics
Folate deficiency
After infection or medication in an African American male + Heinz Bodies and Bite
Cells on smear. Flare triggers: Fava beans, antimalarials, sulfonamides
G6PD deficiency
History of jaundice, transfusion, new medication or infection (+) direct coombs
test
Autoimmune Hemolytic anemia
↓ MCV (microcytic), ↑ TIBC, ↓ Ferritin (low iron stores) ↓ MCH (hypochromic).
Associated with pica and nail spooning, target cells
Iron deficiency
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Physician Assistant National Certifying Exam