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Simmons NURP 502 Exam 1: Metabolic Syndrome

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This deck covers key concepts and screening guidelines related to metabolic syndrome, particularly in children and adolescents, as outlined in the Simmons NURP 502 course.

Name the components of metabolic syndrome.

• Abdominal obesity • Insulin resistance +/- glucose intolerance • HTN • Atherogenic dyslipidemia / Hyperlipidemia • Proinflammatory state • Prothrombic state
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Key Terms

Term
Definition
Name the components of metabolic syndrome.
• Abdominal obesity • Insulin resistance +/- glucose intolerance • HTN • Atherogenic dyslipidemia / Hyperlipidemia • Proinflammatory state • Prothromb...
When should screening for risk factors for CV dx begin?
2 yo
Starting at age 2, what is done at office visits for CV risk?
• Graph BMI by percentile • Identify overweight/obese • Lipids (if risk factors)
When do you start screening glucose?
• Screen if overweight, family history, or hypertensive • Otherwise at age 10
How is obesity (metabolic syndrome) defined in children <10 yo?
• WC >90th percentile • BMI >85th percentile
T/F Below the age of 10, metabolic syndrome is not a diagnosis.
True. However, NIH now has reference ranges for triglycerides for metabolic syndrome at this age.

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TermDefinition
Name the components of metabolic syndrome.
• Abdominal obesity • Insulin resistance +/- glucose intolerance • HTN • Atherogenic dyslipidemia / Hyperlipidemia • Proinflammatory state • Prothrombic state
When should screening for risk factors for CV dx begin?
2 yo
Starting at age 2, what is done at office visits for CV risk?
• Graph BMI by percentile • Identify overweight/obese • Lipids (if risk factors)
When do you start screening glucose?
• Screen if overweight, family history, or hypertensive • Otherwise at age 10
How is obesity (metabolic syndrome) defined in children <10 yo?
• WC >90th percentile • BMI >85th percentile
T/F Below the age of 10, metabolic syndrome is not a diagnosis.
True. However, NIH now has reference ranges for triglycerides for metabolic syndrome at this age.
How is metabolic syndrome defined in the 10-16 yo age range?
• WC >90th percentile or adult cut off • Triglycerides >150 • HDL <40 • BP >130 or >85 • FPG >100 or known DMT2
When would you perform an oral GTT?
If FPG >100-125 and DMT2 not known (age range 10-16)
How is metabolic syndrome defined in the 16+ age range?
• WC >94 cm for males • WC >80 cm for females • Triglycerides >150 or treated • HDL <40 males, <50 females, or treated • BP >130 or >85 or treated • FPG: >100 or known DMT2
T/F In children, it is better to look at all non-HDL lipids together than just LDL and triglycerides alone.
True
What are total cholesterol ranges for children?
• Normal <170 • Borderline 170-199 • High 200+
What are LDL ranges for children?
• Normal <110 • Borderline 110-129 • High 130+
Name 7 clinical outcomes of metabolic syndrome.
1. CV dx 2. DMT2 3. PCOS 4. Fatty liver 5. Cholesterol gall stones 6. Asthma 7. Sleep disturbances / Sleep apnea
When should lipid screening be done universally?
• Between ages 9-11 • Again at 17+
Who should receive liver function testing?
• High cholesterol • Obesity
What are interventions for preventing metabolic syndrome?
1. Review BMI with all patients at all well visits, including trends. 2. Positive reinforcement for positive lifestyle changes (and don’t dwell on the chart, if (+) lifestyle changes are being made!). 3. Set reasonable, clear goals. 4. Follow up in primary care on goals set. 5. Lab screening annually, more often if abnormal. 6. Community referrals – know what is available to you and use them! Nutritionist, Exercise programs, Multidisciplinary programs.