StudyXY
RegisterLog in

Comprehensive Guide to Addiction Medications and T

This detailed chart outlines key addiction medications, their indications, neurotransmitter targets, side effects, dosing, and special considerations for age, pregnancy, and breastfeeding in the treatment of opioid and alcohol dependence.

Mason Bennett
Contributor
4.6
42
4 months ago
Preview (2 of 5 Pages)
100%
Purchase to unlock

Page 1

Comprehensive Guide to Addiction Medications and T - Page 1 preview image

Loading page image...

Addiction Medications TableWeek BCH O WBl. M NH M V n t M T V“HIS ASSIGNMENT SHOULD BE SUBMITTED TO THE WEEK 5 MEDICATION TABLE DROPBOX BY SUNDAY AT 11 59 P.M. MT.Drug NameIndicationNeurotransmitterfs)AffectedTarget SymptomsHalf-life (Tl'2),Metabolism (CYP 450enzyme)Notable Side Effects(link to NT or affectedbrain circuit)Initial DosingConsiderationsSpecific lifespanconsiderations(age, pregnancy,breastfeeding)Buprenorphine(Subutex)Indication:Maintenancetreatment of opioiddependenceMaintenancetreatment of opioiddependence inpatients who haveachieved andsustained prolongedclinical stability onlow-to moderatedoses of a transmucosalbuprenorphinecontaining productModerate to severeopioid use disorder inpatients who haveinitiated treatmentwith a transmucosal24-42hoursCYP450:CYP3A424-42hoursCYP450:CYP3A4Half-life: 24-42 hoursCYP450: CYP3A4Headache,constipation, nauseaOral hypoesthesia,glosscdyniaOrthostatichypotensionRespiratory distressHepatotoxicityBinds to mu opioidreceptorsInitial dosing:Sublingual 8-32mg dayControlled studieshave not beenconducted inpregnant women.Buprenorphinemay be preferableto methadone inpregnant women.Neonatal opioidwithdrawalsyndrome has beenreported followinguse ofBuprenorphineduring pregnancySome drag isbuprenorphinecontaining product,followed by doseadjustment for aminimum of 7 daysNeurotransmitteraffected: Mu opioidreceptor partialagonist Antagonist atthe kappa opioidreceptorTarget symptoms:Opioid dependencefound in mother'sbreast milk.Recommendedeither todiscontinued drugor formula feed.Use with cautionin elderly. Somepatients maytolerate lowerdoses better.Buprenorphine Naloxone(Suboxone, Zubsolv,Bunavail)Indication:Treatment, andmaintenance ofopioid dependence.Induction oftreatment for opioiddependenceMaintenancetreatment of opioiddependence inpatients who haveachieved andsustained prolongedclinical stability onlow-to moderateSuboxone: 24-42 hoursNaloxone: 2-12 hoursCYP450: CYP3A4Headache,constipation, nausea,oral hypcesthesia,glosscdynia,orthostatichypotension, sedationBinding at mu opioidreceptorsInitial dosing:Bunavail: Day 1:induction dose:Initial: Buccal:Buprenorphine 2.1mg naloxone 0.3mg; may repeatdose after 2 hours,based on control ofacute withdrawalsymptoms;maximum totaldose:buprenorphine 4.2mg naloxone 0.7mg. Day 2:

Page 2

Comprehensive Guide to Addiction Medications and T - Page 2 preview image

Loading page image...

doses of a transmucosalNeurotransmitters:Antagonist at thekappa opioid receptorMu opioid receptorpartial agonistTarget symptoms:Opioid dependenceinduction dose: Upto buprenorphine8.4 mg naloxone1.4 mg as a singledose Suboxone:Day 1: inductiondose: Initial:Sublingual:Buprenorphine 2mg naloxone 0.5mg orbuprenorphine 4mg naloxone 1mg; may titratedose, based oncontrol of acutewithdrawalsymptoms, inbuprenorphine 2mg naloxone 0.5mg orbuprenorphine 4mg naloxone 1 mgincrementsapproximatelyevery 2 hours up toa total dose ofbuprenorphine 8mg naloxone 2mg. Day 2:induction dose:Sublingual: Up tobuprenorphine 16mg naloxone 4 mgas a single dose.Zubsolv: Day 1:induction dose:Sublingual: Stanwith an initial doseof buprenorphine1.4 mg naloxoneC.36 mg; based oncontrol of acutewithdrawalsymptoms, mayadministeradditional doses inincrements of 1 to2 buprenorphine1.4 mg naloxoneC.36 mg tabletsevery 1.5 to 2hours to a total day1 dose up tobuprenorphine 5.7mg naloxone 1.4mg. Some patients(eg, those withrecent exposure tobuprenorphine)may tolerate up tobuprenorphine 4.2mg naloxone 1.08mg as a single,
Preview Mode

This document has 5 pages. Sign in to access the full document!

Study Now!

XY-Copilot AI
Unlimited Access
Secure Payment
Instant Access
24/7 Support
Document Chat

Document Details

Subject
Pharmacology

Related Documents

View all
Class Notes

Med and Patho

Comprehensive drug profiles for Sumatriptan (Imitrex), Acetaminophen (Tylenol), and others—covering classification, uses, dosages, interactions, adverse effects, nursing implications, and patient teaching. Ideal for nursing and pharmacology study.

Past Exams

NSG318 Drug Calculation Medication Math Competency

Math competency practice for nursing students, including rounding decimals, metric conversions (mL, L, tsp, Tbsp), and weight conversions between pounds and kilograms. Useful for dosage calculations and clinical accuracy.

Class Notes

Pharm Quiz Cholestorol

Patient education summary on Lipitor (atorvastatin): includes dosage, timing, food interactions (grapefruit, high-fat foods), and key side effects like muscle pain. Emphasizes consistency and monitoring for adverse reactions.

Class Presentation

MHACB599 Video Presentation

This presentation explores the opioid overdose crisis, highlighting causes like over prescription and lack of education. It proposes a dedicated department to educate the public, train professionals, and reduce opioid-related deaths.

Past Exams

Pharmacological and Parenteral Therapies

This quiz reviews essential pharmacology concepts, including drug absorption, routes of administration, drug interactions, and medication functions—ideal for nursing and medical students preparing for exams like NCLEX or USMLE.

Past Exams

Pharm Unit 6 Book Quiz

Unit 6 quiz on GI medications for APNs, covering mechanisms of action for loperamide and best laxative choices post-surgery. Includes rationales for selecting appropriate pharmacologic treatments. Ideal for advanced nursing pharmacology review.

Past Exams

NUR 2474 Pharmacology Final Exam NCLEX Style Pract

High-yield pharmacology questions covering insulin types, diabetes management, hypothyroidism in pregnancy, and med safety. Perfect for med-surg and NCLEX prep. Sharpen your clinical judgment now.

Solved Assignments

Evaluating Pharmaceutical Patents: Challenges in Drug Marketing, Accessibility, and Cost Recovery

Assignment analyzing the complexities of pharmaceutical patents and their effects on drug marketing.

Exam Guides

Test Bank For Integrated Cardiopulmonary Pharmacology, 3rd Edition, 3rd Edition

Let Test Bank For Integrated Cardiopulmonary Pharmacology, 3rd Edition, 3rd Edition be your exam guide, filled with practice questions and solutions that make studying easier.

Exam Guides

Test Bank For Core Concepts in Pharmacology, 3rd Edition

Boost your study sessions with Test Bank For Core Concepts in Pharmacology, 3rd Edition, a practical guide featuring exam questions and answers.