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Question 1 4 / 4 points
A potentially life-threatening adverse response to angiotensin-converting enzyme inhibitors is
angioedema. Which of the following statements is true about this adverse response?
Question options:
Swelling of the tongue or hoarseness are the most common symptoms.
It appears to be related to the decrease in aldosterone production.
Presence of a dry, hacky cough indicates a high risk for this adverse response.
Because it takes time to build up a blood level, it occurs after being on the drug for about 1
week.
Question 2 4 / 4 points
Jamison has been prescribed citalopram (Celexa) to treat his depression. Education regarding
how quickly selective serotonin reuptake inhibitor (SSRI) antidepressants work would be:
Question options:
Appetite and concentration improve in the first 1 to 2 weeks.
Sleep should improve almost immediately upon starting citalopram.
Full response to the SSRI may take 2 to 4 months after he reaches the full therapeutic dose.
His dysphoric mood will improve in 1 to 2 weeks.
Question 3 4 / 4 points
Larry is taking allopurinol to prevent gout. Monitoring of a patient who is taking allopurinol
includes:
Question options:
Complete blood count
Blood glucose
C-reactive protein
BUN, creatinine, and creatinine clearance
Question 4 4 / 4 points
When a pharmacoeconomic analysis looks at two or more treatment alternatives that are
considered equal in efficacy and compares the costs of each it is referred to as:
Question options:

Cost-minimization analysis
Cost-of-illness analysis
Cost-effectiveness analysis
Cost-benefit analysis
Question 5 4 / 4 points
Being competent in the use of information technology in clinical practice is expected in
professional nurses. Advanced practice competence includes the ability to:
Question options:
Search for information using the most common search engines
Serve as content experts in developing, implementing, and evaluating information Systems
Write programs to assure the integrity of health information
Use information technology to prescribe drugs
Question 6 4 / 4 points
Instructions for the use of nicotine gum include:
Question options:
Chew the gum quickly to get a peak effect.
The gum should be “parked” in the buccal space between chewing.
Acidic drinks such as coffee help with the absorption of the nicotine.
The highest abstinence rates occur if the patient chews the gum when he or she is having
cravings.
Question 7 4 / 4 points
A laboratory result indicates that the peak level for a drug is above the minimum toxic
concentration. This means that the:
Question options:
Concentration will produce therapeutic effects
Concentration will produce an adverse response
Time between doses must be shortened
Duration of action of the drug is too long
Question 8 4 / 4 points

An acceptable first-line treatment for peptic ulcer disease with positive H. pylori test is:
Question options:
Histamine2 receptor antagonists for 4 to 8 weeks
Proton pump inhibitor bid for 12 weeks until healing is complete
Proton pump inhibitor bid plus clarithromycin plus amoxicillin for 14 days
Proton pump inhibitor bid and levofloxacin for 14 days
Question 9 4 / 4 points
Alterations in drug metabolism among Asians may lead to:
Question options:
Slower metabolism of antidepressants, requiring lower doses
Faster metabolism of neuroleptics, requiring higher doses
Altered metabolism of omeprazole, requiring higher doses
Slower metabolism of alcohol, requiring higher doses
Question 10 4 / 4 points
Patients who are prescribed exogenous androgens need to be warned that decreased libido:
Question options:
Is an unusual side effect of androgens and should be reported to the provider
Is treated with increased doses of androgens, so the patient should let the provider know if he
is having problems
May be a sign of early prostate cancer and he should make an appointment for a prostate
screening exam
May occur with androgen therapy
Question 11 0 / 4 points
A woman who is pregnant and has hyperthyroidism is best managed by a specialty team who
will most likely treat her with:
Question options:
Methimazole
Propylthiouracil (PTU)
Radioactive iodine

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Nothing, treatment is best delayed until after her pregnancy ends
Question 12 4 / 4 points
The dosage of Vitamin B12 to initially treat pernicious anemia is:
Question options:
Nasal cyanocobalamin 1 gram spray in each nostril daily x 1 week then weekly x 1 month
Vitamin B12 IM monthly
Vitamin B12 1,000 mcg IM daily x 1 week then 1,000 mg IM weekly for a month
Oral cobalamin 1,000 mcg daily
Question 13 4 / 4 points
A provider may consider testing for CYP2D6 variants prior to starting tamoxifen for breast
cancer to:
Question options:
Ensure the patient will not have increased adverse drug reactions to the tamoxifen
Identify potential drug-drug interactions that may occur with tamoxifen
Reduce the likelihood of therapeutic failure with tamoxifen treatment
Identify poor metabolizers of tamoxifen
Question 14 4 / 4 points
Disease states in addition to hypertension in which beta blockade is a compelling indication for
the use of beta blockers include:
Question options:
Heart failure
Angina
Myocardial infarction
Dyslipidemia
Question 15 4 / 4 points
Developmental variation in renal function has what impact on prescribing for infants and
children?
Question options:
Lower doses of renally excreted drugs may be prescribed to infants younger than age 6 months.

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Higher doses of water soluble drugs may need to be prescribed because of increased renal
excretion.
Renal excretion rates have no impact on prescribing.
Parents need to be instructed on whether drugs are renally excreted or not.
Question 16 4 / 4 points
Allison is an 18-year-old college student with type 1 diabetes. She is on NPH twice daily and
Novolog before meals. She usually walks for 40 minutes each evening as part of her exercise
regimen. She is beginning a 30-minute swimming class three times a week at 1 p.m. What is
important for her to do with this change in routine?
Question options:
Delay eating the midday meal until after the swimming class.
Increase the morning dose of NPH insulin on days of the swimming class.
Adjust the morning insulin injection so that the peak occurs while swimming.
Check glucose level before, during, and after swimming.
Question 17 4 / 4 points
Sophie presents to the clinic with a malodorous vaginal discharge and is confirmed to have
Trichomonas infection. Treatment for her would include:
Question options:
Metronidazole 2 grams PO x 1 dose
Topical intravaginal metronidazole daily x 7 days
Intravaginal clindamycin daily x 7 days
Azithromycin 2 grams PO x 1 dose
Question 18 4 / 4 points
True contraindications to diphtheria, tetanus, and acellular pertussis (DTaP or Tdap) vaccine
include:
Question options:
Fever up to 104oF (40.5oC) after previous DTaP vaccine
Family history of seizures after DTaP vaccine
Adolescent pregnancy
Anaphylactic reaction with a previous dose

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Question 19 4 / 4 points
Patients who have a poor metabolism phenotype will have:
Question options:
Slowed metabolism of a prodrug into an active drug, leading to accumulation of Prodrug
Accumulation of inactive metabolites of drugs
A need for increased dosages of medications
Increased elimination of an active drug
Question 20 4 / 4 points
The role of the NP in the use of herbal medication is to:
Question options:
Maintain competence in the prescribing of common herbal remedies
Recommend common over-the-counter herbs to patients
Educate patients and guide them to appropriate sources of care
Encourage patients to not use herbal therapy due to the documented dangers
Question 21 4 / 4 points
Vicky, age 56 years, comes to the clinic requesting a refill of her Fiorinal (aspirin and butalbital)
that she takes for migraines. She has been taking this medication for over 2 years for migraines
and states one dose usually works to abort her migraine. What is the best care for her?
Question options:
Switch her to sumatriptan (Imitrex) to treat her migraines.
Assess how often she is using Fiorinal and refill her medication.
Switch her to a beta blocker such as propranolol to prevent her migraine.
Request she return to the original prescriber of Fiorinal as you do not prescribe butalbital for
migraines.
Question 22 4 / 4 points
Ginseng, which is taken to assist with memory, may potentiate:
Question options:
Aricept
Insulin

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Digoxin
Propranolol
Question 23 4 / 4 points
The most cost-effective treatment for two or three impetigo lesions on the face is:
Question options:
Mupirocin ointment
Retapamulin (Altabax) ointment
Topical clindamycin solution
Oral amoxicillin/clavulanate (Augmentin)
Question 24 4 / 4 points
The reason that two MMR vaccines at least a month apart are recommended is:
Question options:
The second dose of MMR “boosts” the immunity built from the first dose.
Two vaccines 1 month apart is the standard dosing for all live virus vaccines.
If the two MMR vaccine doses are given too close together there is a greater likelihood of
severe localized reaction to the vaccine.
Only 95% of patients are fully immunized for measles after the first vaccine, with 99% having
immunity after two doses of MMR.
Question 25 4 / 4 points
The first-line therapy for mild-persistent asthma is:
Question options:
High-dose montelukast
Theophylline
Low-dose inhaled corticosteroids
Long-acting beta-2-agonists
Question 26 4 / 4 points
The benefits to the patient of having an Advanced Practice Registered Nurse (APRN) prescriber
include:
Question options:

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Nurses know more about Pharmacology than other prescribers because they take it both in
their basic nursing program and in their APRN program.
Nurses care for the patient from a holistic approach and include the patient in decision making
regarding their care.
APRNs are less likely to prescribe narcotics and other controlled substances.
APRNs are able to prescribe independently in all states, whereas a physician’s assistant needs to
have a physician supervising their practice.
Question 27 4 / 4 points
Which the following persons should not have a statin medication ordered?
Question options:
Someone with 3 first- or second-degree family members with history of muscle issues when
started on statins
Someone with high lipids, but low BMI
Premenopausal woman with recent history of hysterectomy
Prediabetic male with known metabolic syndrome
Question 28 4 / 4 points
Azithromycin dosing requires that the first day’s dosage be twice those of the other 4 days of
the prescription. This is considered a loading dose. A loading dose:
Question options:
Rapidly achieves drug levels in the therapeutic range
Requires four- to five-half-lives to attain
Is influenced by renal function
Is directly related to the drug circulating to the target tissues
Question 29 4 / 4 points
An Investigational New Drug is filed with the U.S. Food and Drug Administration:
Question options:
When the manufacturer has completed phase III trials
When a new drug is discovered
Prior to animal testing of any new drug entity

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MN553 Final Exam Quiz with Answers (97 Solved Questions)

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