Pharmacology Midterm Exam with Answers (51 Solved Questions)
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Question 1Which drug below has an interaction with cigarette smoking and should be adjustedbased on patient’s tobacco use/non-use?ResponseFeedback:“Clozapine blood levels are significantly lowered by cigarettesmoking and by other hepatic enzyme-inducers.”Question 2Which of the following medications is best to AVOID in maintenance treatment of bipolardisorder and why?ResponseFeedback:“As noted previously, antidepressants may contribute to anincrease in mood episode frequency.”Question 3Glia cells play a supportive role in the neuron. A few of the functions of the glial cellsinclude providing nutrition, maintaining homeostasis, stabilizing synapses, andmyelinating axons. The glial cells are categorized as microglia or macroglia. Of themacroglia cells, which one plays a role in myelinating axons, which may contribute tomood disorders if altered?Question 4Which of the following are NOT primary target(s) symptom for antipsychotic agents inschizophrenia?i.Depression, anxiety, demoralization, suicidality, excitability, and agitationii.Delusions, hallucinations, disorganized thoughtsiii.Affective flattening, alogia, avolition, anhedonia, social withdrawaliv.Attention, memory, and executive functionsResponseFeedback:“For schizophrenia, the primary target symptoms for antipsychoticagents fall into three categories: psychotic symptoms (e.g.,hallucinations, delusions, disorganization); agitation (e.g., distractibility,affective lability, tension, increased motor activity); and negativesymptoms (e.g. apathy, diminished affect, social withdrawal, poverty ofspeech.” AND “Although cognitive deficits are an important contributorto disability in schizophrenia, cognitive deficits usually are notconsidered a target for antipsychotic agents because they are not veryresponsible to current agents.”Question 5A 32-year-old males calls you complaining of decreased libido since starting Paroxetine20 mg 2 weeks ago. He reported stopping the medication 1 day ago and is nowexperiencing extreme irritability and nervousness. He wishes to stop this medication dueto side effects. What do you recommend?ResponseFeedback:under selective serotonin re-uptake inhibitors discontinuation syndromesubtitle: “The risk of such adverse events occurring seems to be
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