Test Bank For Lehne's Pharmacology for Nursing Care, 10th Edition

Name: Test Bank For Lehne's Pharmacology for Nursing Care, 10th Edition
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Author: Eli Simmons

Test Bank For Lehne's Pharmacology for Nursing Care, 10th Edition provides a strong foundation in exam topics with a balance of theoretical knowledge and practical application.

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Chapter 01: Orientation to Pharmacology
Test Bank
MULTIPLE CHOICE
1. The nurse is teaching a patient how a medication works to treat an illness. To do this, the nurse
will rely on knowledge of which topic?
a. Clinical pharmacology
b. Drug efficacy
c. Pharmacokinetics
d. Pharmacotherapeutics
ANS: D
Pharmacotherapeutics is the study of the use of drugs to diagnose, treat, and prevent conditions.
Clinical pharmacology is concerned with all aspects of drug-human interactions. Drug efficacy
measures the extent to which a given drug causes an intended effect. Pharmacokinetics is the
study of the impact of the body on a drug.
PTS: 1 DIF: Cognitive Level: Comprehension REF: p. 1
TOP: Nursing Process: Implementation
MSC: NCLEX Client Needs Category: Physiologic Integrity: Pharmacologic and Parenteral Therapies
2. What is a desired outcome when a drug is described as easy to administer?
a. It can be stored indefinitely without need
for refrigeration.
b. It does not interact significantly with other
medications.
c. It enhances patient adherence to the drug
regimen.
d. It is usually relatively inexpensive to
produce.
ANS: C
A major benefit of drugs that are easy to administer is that patients taking them are more likely to
comply with the drug regimen. Drugs that are easy to give may have the other attributes listed,
but those properties are independent of ease of administration.
PTS: 1 DIF: Cognitive Level: Comprehension REF: p. 2
TOP: Nursing Process: Assessment
MSC: NCLEX Client Needs Category: Physiologic Integrity: Pharmacologic and Parenteral Therapies
3. A patient tells the nurse that an analgesic he will begin taking may cause drowsiness and will
decrease pain up to 4 hours at a time. Based on this understanding of the drug’s effects by the
patient, the nurse will anticipate which outcome?

a. Decreased chance of having a placebo
effect
b. Decreased motivation to take the drug
c. Improved compliance with the drug
regimen
d. Increased likelihood of drug overdose
ANS: C
A drug is effective if it produces the intended effects, even if it also produces side effects.
Patients who understand both the risks and benefits of taking a medication are more likely to
comply with the drug regimen.
PTS: 1 DIF: Cognitive Level: Comprehension REF: p. 2
TOP: Nursing Process: Evaluation
MSC: NCLEX Client Needs Category: Physiologic Integrity: Pharmacologic and Parenteral Therapies
MULTIPLE RESPONSE
1. What are the properties of an ideal drug? (Select all that apply.)
a. Irreversible action
b. Predictability
c. Ease of administration
d. Chemical stability
e. A recognizable trade name
ANS: B, C, D
In addition to predictability, ease of administration, and chemical stability, other properties
include a reversible action so that any harm the drug may cause can be undone and a simple
generic name, because generic names are usually complex and difficult to remember and
pronounce.
PTS: 1 DIF: Cognitive Level: Comprehension REF: pp. 1-2
TOP: Nursing Process: Assessment
MSC: NCLEX Client Needs Category: Physiologic Integrity: Pharmacologic and Parenteral Therapies
2. Before administering a medication, what does the nurse need to know to evaluate how individual
patient variability might affect the patient’s response to the medication? (Select all that apply.)
a. Chemical stability of the medication
b. Ease of administration
c. Family medical history
d. Patient’s age
e. Patient’s diagnosis

ANS: C, D, E
The family medical history can indicate genetic factors that may affect a patient’s response to a
medication. Patients of different ages can respond differently to medications. The patient’s
illness can affect how drugs are metabolized. The chemical stability of the medication and the
ease of administration are properties of drugs.
PTS: 1 DIF: Cognitive Level: Analysis REF: pp. 3-4
TOP: Nursing Process: Implementation
MSC: NCLEX Client Needs Category: Physiologic Integrity: Reduction of Risk Potential

Chapter 02: Application of Pharmacology in Nursing Practice
Test Bank
MULTIPLE CHOICE
1.A patient is using a metered-dose inhaler containing albuterol for asthma. The medication label
instructs the patient to administer “2 puffs every 4 hours as needed for coughing or wheezing.”
The patient reports feeling jittery sometimes when taking the medication, and she doesn’t feel
that the medication is always effective. Which action is outside the nurse’s scope of practice?
a. Asking the patient to demonstrate use of
the inhaler
b. Assessing the patient’s exposure to
tobacco smoke
c. Auscultating lung sounds and obtaining
vital signs
d. Suggesting that the patient use one puff to
reduce side effects
ANS: D
It is not within the nurse’s scope of practice to change the dose of a medication without an order
from a prescriber. Asking the patient to demonstrate inhaler use helps the nurse to evaluate the
patient’s ability to administer the medication properly and is part of the nurse’s evaluation.
Assessing tobacco smoke exposure helps the nurse determine whether nondrug therapies, such a
smoke avoidance, can be used as an adjunct to drug therapy. Performing a physical assessment
helps the nurse evaluate the patient’s response to the medication.
PTS: 1 DIF: Cognitive Level: Application REF: pp. 9-10
TOP: Nursing Process: Implementation
MSC: NCLEX Client Needs Category: Physiologic Integrity: Pharmacologic and Parenteral Therapies
2. A postoperative patient is being discharged home with acetaminophen/hydrocodone [Lortab] for
pain. The patient asks the nurse about using Tylenol for fever. Which statement by the nurse is
correct?
a. “It is not safe to take over-the-counter
drugs with prescription medications.”
b. “Taking the two medications together
poses a risk of drug toxicity.”
c. “There are no known drug interactions, so
this will be safe.”
d. “Tylenol and Lortab are different drugs,
so there is no risk of overdose.”
ANS: B
Tylenol is the trade name and acetaminophen is the generic name for the same medication. It is

important to teach patients to be aware of the different names for the same drug to minimize the
risk of overdose. Over-the-counter (OTC) medications and prescription medications may be
taken together unless significant harmful drug interactions are possible. Even though no drug
interactions are at play in this case, both drugs contain acetaminophen, which could lead to
toxicity.
PTS: 1 DIF: Cognitive Level: Application REF: p. 8
TOP: Nursing Process: Implementation
MSC: NCLEX Client Needs Category: Physiologic Integrity: Reduction of Risk Potential
3. The nurse is preparing to care for a patient who will be taking an antihypertensive medication.
Which action by the nurse is part of the assessment step of the nursing process?
a. Asking the prescriber for an order to
monitor serum drug levels
b. Monitoring the patient for drug
interactions after giving the medication
c. Questioning the patient about
over-the-counter medications
d. Taking the patient’s blood pressure
throughout the course of treatment
ANS: C
The assessment part of the nursing process involves gathering information before beginning
treatment, and this includes asking about other medications the patient may be taking.
Monitoring serum drug levels, watching for drug interactions, and checking vital signs after
giving the medication are all part of the evaluation phase.
PTS: 1 DIF: Cognitive Level: Application REF: p. 6
TOP: Nursing Process: Assessment
MSC: NCLEX Client Needs Category: Physiologic Integrity: Reduction of Risk Potential
4. A postoperative patient reports pain, which the patient rates as an 8 on a scale from 1 to 10 (10
being the most extreme pain). The prescriber has ordered acetaminophen [Tylenol] 650 mg PO
every 6 hours PRN pain. What will the nurse do?
a. Ask the patient what medications have
helped with pain in the past.
b. Contact the provider to request a different
analgesic medication.
c. Give the pain medication and reposition
the patient to promote comfort.
d. Request an order to administer the
medication every 4 hours.
ANS: B
The nursing diagnosis for this patient is severe pain. Acetaminophen is given for mild to

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moderate pain, so the nurse should ask the prescriber to order a stronger analgesic medication.
Asking the patient to tell the nurse what has helped in the past is part of an initial assessment and
should be done preoperatively and not when the patient is having severe pain. Because the
patient is having severe pain, acetaminophen combined with nondrug therapies will not be
sufficient. Increasing the frequency of the dose of a medication for mild pain will not be
effective.
PTS: 1 DIF: Cognitive Level: Analysis REF: p. 9
TOP: Nursing Process: Diagnosis
MSC: NCLEX Client Needs Category: Physiologic Integrity: Pharmacologic and Parenteral Therapies
5. A patient newly diagnosed with diabetes is to be discharged from the hospital. The nurse
teaching this patient about home management should begin by doing what?
a. Asking the patient to demonstrate how to
measure and administer insulin
b. Discussing methods of storing insulin and
discarding syringes
c. Giving information about how diet and
exercise affect insulin requirements
d. Teaching the patient about the long-term
consequences of poor diabetes control
ANS: A
Because insulin must be given correctly to control symptoms and because an overdose can be
fatal, it is most important for the patient to know how to administer it. Asking for a
demonstration of technique is the best way to determine whether the patient has understood the
teaching. When a patient is receiving a lot of new information, the information presented first is
the most likely to be remembered. The other teaching points are important as well, but they are
not as critical and can be taught later.
PTS: 1 DIF: Cognitive Level: Application REF: p. 9
TOP: Nursing Process: Planning
MSC: NCLEX Client Needs Category: Physiologic Integrity: Reduction of Risk Potential
6. The nurse receives an order to give morphine 5 mg IV every 2 hours PRN pain. Which action is
not part of the six rights of drug administration?
a. Assessing the patient’s pain level 15 to 30
minutes after giving the medication
b. Checking the medication administration
record to see when the last dose was
administered
c. Consulting a drug manual to determine
whether the amount the prescriber ordered
is appropriate

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d. Documenting the reason the medication
was given in the patient’s electronic
medical record
ANS: A
Assessing the patient’s pain after administering the medication is an important part of the nursing
process when giving medications, but it is not part of the six rights of drug administration.
Checking to see when the last dose was given helps ensure that the medication is given at the
right time. Consulting a drug manual helps ensure that the medication is given in the right dose.
Documenting the reason for a pain medication is an important part of the right
documentation—the sixth right.
PTS: 1 DIF: Cognitive Level: Application REF: p. 9
TOP: Nursing Process: Implementation
MSC: NCLEX Client Needs Category: Physiologic Integrity: Reduction of Risk Potential
7. A patient tells a nurse that a medication prescribed for recurrent migraine headaches is not
working. What will the nurse do?
a. Ask the patient about the number and
frequency of tablets taken.
b. Assess the patient’s headache pain on a
scale from 1 to 10.
c. Report the patient’s complaint to the
prescriber.
d. Suggest biofeedback as an adjunct to drug
therapy.
ANS: A
When evaluating the effectiveness of a drug, it is important to determine whether the patient is
using the drug as ordered. Asking the patient to tell the nurse how many tablets are taken and
how often helps the nurse determine compliance. Assessing current pain does not yield
information about how well the medication is working unless the patient is currently taking it.
The nurse should gather as much information about compliance, symptoms, and drug
effectiveness as possible before contacting the prescriber. Biofeedback may be an effective
adjunct to treatment, but it should not be recommended without complete information about drug
effectiveness.
PTS: 1 DIF: Cognitive Level: Application REF: p. 9
TOP: Nursing Process: Evaluation
MSC: NCLEX Client Needs Category: Physiologic Integrity: Pharmacologic and Parenteral Therapies
8. A nurse is preparing to administer medications. Which patient would the nurse consider to have
the greatest predisposition to an adverse reaction?
a. A 30-year-old man with kidney disease
b. A 75-year-old woman with cystitis

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c. A 50-year-old man with an upper
respiratory tract infection
d. A 9-year-old boy with an ear infection
ANS: A
The individual with impaired kidney function would be at risk of having the drug accumulate to
a toxic level because of potential excretion difficulties. Cystitis is an infection of the bladder and
not usually the cause of excretion problems that might lead to an adverse reaction from a
medication. A respiratory tract infection would not predispose a patient to an adverse reaction,
because drugs are not metabolized or excreted by the lungs. A 9-year-old boy would not have the
greatest predisposition to an adverse reaction simply because he is a child; nor does an ear
infection put him at greater risk.
PTS: 1 DIF: Cognitive Level: Analysis REF: p. 9
TOP: Nursing Process: Planning
MSC: NCLEX Client Needs Category: Physiologic Integrity: Reduction of Risk Potential
9. A nurse consults a drug manual before giving a medication to an 80-year-old patient. The manual
states that older-adult patients are at increased risk for hepatic side effects. Which action by the
nurse is correct?
a. Contact the provider to discuss an order
for pretreatment laboratory work.
b. Ensure that the drug is given in the correct
dose at the correct time to minimize the
risk of adverse effects.
c. Notify the provider that this drug is
contraindicated for this patient.
d. Request an order to give the medication
intravenously so that the drug does not
pass through the liver.
ANS: A
The drug manual indicates that this drug should be given with caution to elderly patients. Getting
information about liver function before giving the drug establishes baseline data that can be
compared with post-treatment data to determine whether the drug is affecting the liver. Giving
the correct dose at the correct interval helps to minimize risk, but without baseline information,
the effects cannot be determined. The drug is not contraindicated.
PTS: 1 DIF: Cognitive Level: Analysis REF: p. 7
TOP: Nursing Process: Implementation
MSC: NCLEX Client Needs Category: Physiologic Integrity: Reduction of Risk Potential
10. A patient has been receiving intravenous penicillin for pneumonia for several days and begins to
complain of generalized itching. The nurse auscultates bilateral wheezing and notes a
temperature of 38.5°C (101°F). Which is the correct action by the nurse?

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a. Administer the next dose and continue to
evaluate the patient’s symptoms.
b. Ask the prescriber if an antihistamine can
be given to relieve the itching.
c. Contact the prescriber to request an order
for a chest radiograph.
d. Hold the next dose and notify the
prescriber of the symptoms.
ANS: D
Pruritus and wheezing are signs of a possible allergic reaction, which can be fatal; therefore, the
medication should not be given and the prescriber should be notified. When patients are having a
potentially serious reaction to a medication, the nurse should not continue giving the medication.
Antihistamines may help the symptoms of an allergic reaction, but the first priority is to stop the
medication. Obtaining a chest radiograph is not helpful.
PTS: 1 DIF: Cognitive Level: Application REF: p. 10
TOP: Nursing Process: Evaluation
MSC: NCLEX Client Needs Category: Physiologic Integrity: Reduction of Risk Potential
11. A postoperative patient has orders for morphine sulfate 1 to 2 mg IV every 1 hour PRN for
severe pain and acetaminophen-hydrocodone [Lortab] 7.5 mg PO every 4 to 6 hours PRN for
moderate pain. The patient reports pain at a level of 8 on a scale of 1 to 10, with 10 being the
worst pain. Which action by the nurse is appropriate?
a. Administer acetaminophen-hydrocodone
7.5 mg PO every 4 hours.
b. Administer acetaminophen-hydrocodone
7.5 mg PO every 6 hours and change to
every 4 hours if not effective.
c. Administer morphine sulfate 1 mg IV
every 1 hour until pain subsides.
d. Administer morphine sulfate 2 mg IV and
evaluate the patient’s pain in 15 to 30
minutes.
ANS: D
With PRN medications, the schedule is not fixed and the administration of these medications
depends on the patient’s condition. It is the nurse’s responsibility to assess the patient’s condition
and then give the appropriate PRN medication. In this case, the patient has severe pain and
should receive MS IV. Either 1 mg or 2 mg may be given, but the nurse must evaluate the
effectiveness of the pain medication within 15 to 30 minutes to help determine subsequent doses.
Acetaminophen-hydrocodone is not appropriate because it is ordered for moderate pain and this
patient reports severe pain. Giving MS IV every hour is not appropriate for a PRN medication
unless the patient’s condition warrants it.

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Chapter 03: Drug Regulation, Development, Names, and Information
Test Bank
MULTIPLE CHOICE
1. A nurse educator is conducting a continuing education class on pharmacology. To evaluate the
learning of the nurses in the class, the nurse educator asks, “Which drug name gives information
about the drug’s pharmacologic classification?” Which is the correct response?
a. Amoxicillin
b. Tylenol
c. Cipro
d. Motrin
ANS: A
Amoxicillin is the generic name, and the suffix “-cillin” indicates that it belongs to the penicillin
class of antibiotics. Tylenol, Cipro, and Motrin are all trade names without segments that
indicate their pharmacologic class.
PTS: 1 DIF: Cognitive Level: Comprehension REF: p. 18
TOP: Nursing Process: Diagnosis
MSC: NCLEX Client Needs Category: Physiologic Integrity: Pharmacologic and Parenteral Therapies
2. The FDA Amendments Act (FDAAA) was passed in 2007 to address which aspect of drug
safety?
a. Allowing pharmaceutical companies to
identify off-label uses of medications
approved for other uses
b. Evaluating drug safety information that
emerges after a drug has been approved
and is in use
c. Expediting the approval process of the
U.S. Food and Drug Administration
(FDA) so that needed drugs can get to
market more quickly
d. Requiring manufacturers to notify patients
before removing a drug from the market
ANS: B
The FDAAA was passed to enable the Food and Drug Administration to continue oversight of a
drug after granting it approval so that changes in labeling could be made as necessary and
postmarketing risks could be tracked and identified. A provision of the FDA Modernization Act
(FDAMA), passed in 1997, allows drug companies to promote their products for off-label uses as
long as they promise to conduct studies to support their claims. Regulations to permit accelerated
approval of drugs for life-threatening diseases were adopted in 1992 by the FDA. The

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requirement that drug companies notify patients 6 months before removing a drug from the
market is a provision of the FDAMA.
PTS: 1 DIF: Cognitive Level: Comprehension REF: pp. 14-15
TOP: Nursing Process: Evaluation
MSC: NCLEX Client Needs Category: Physiologic Integrity: Pharmacologic and Parenteral Therapies
3. A nursing student asks a nurse about pharmaceutical research and wants to know the purpose of
randomization in drug trials. The nurse explains that randomization is used to do what?
a. To ensure that differences in outcomes are
the result of treatment and not differences
in subjects
b. To compare the outcome caused by the
treatment to the outcome caused by no
treatment
c. To make sure that researchers are unaware
of which subjects are in which group
d. To prevent subjects from knowing which
group they are in and prevent
preconception bias
ANS: A
Randomization helps prevent allocation bias, which can occur when researchers place subjects
with desired characteristics in the study group and other subjects in the control group so that
differences in outcome are actually the result of differences in subjects and not treatment.
Comparing treatment outcome to no treatment outcome is the definition of a controlled study.
The last two options describe the use of blinding in studies; blinding ensures that researchers or
subjects (or both) are unaware of which subjects are in which group so that preconceptions about
benefits and risks cannot bias the results.
PTS: 1 DIF: Cognitive Level: Comprehension REF: pp. 15-16
TOP: Nursing Process: Implementation
MSC: NCLEX Client Needs Category: Physiologic Integrity: Pharmacologic and Parenteral Therapies
4. Someone asks a nurse about a new drug that is in preclinical testing and wants to know why it
cannot be used to treat a friend’s illness. Which statement by the nurse is correct?
a. “A drug at this stage of development can
be used only in patients with serious
disease.”
b. “At this stage of drug development, the
safety and usefulness of the medication is
unknown.”
c. “Clinical trials must be completed to make
sure the drug is safe to use in humans.”

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d. “Until postmarketing surveillance data are
available, the drug cannot be used.”
ANS: B
Preclinical testing must be completed before drugs can be tested in humans. In this stage, drugs
are evaluated for toxicities, pharmacokinetic properties, and potentially useful effects. Some
drugs can be used in patients before completion of Phase III studies, but this is after preclinical
testing is complete. Clinical trials proceed in stages, and each stage has guidelines defining how
a new drug may be used and which patients may receive it. Postmarketing surveillance takes
place after a drug is in general use.
PTS: 1 DIF: Cognitive Level: Comprehension REF: p. 16
TOP: Nursing Process: Implementation
MSC: NCLEX Client Needs Category: Physiologic Integrity: Reduction of Risk Potential
5. A patient asks a nurse why drugs that have been approved by the FDA still have unknown side
effects. What will the nurse tell the patient?
a. Testing for all side effects of a medication
would be prohibitively expensive.
b. Patients in drug trials often are biased by
their preconceptions of a drug’s benefits.
c. Researchers tend to conduct studies that
will prove the benefits of their new drugs.
d. Subjects in drug trials do not always
represent the full spectrum of possible
patients.
ANS: D
All drug trials are limited by a relatively small group of subjects who may not have all the
characteristics of people who will be using the drug; therefore, some side effects go undetected
until the drug is in use. Although drug trials are very expensive, this is only an indirect reason
they do not detect all side effects before approval. In theory, well-designed drug trials, using
blinded studies, minimize or eliminate subject bias. Designing studies to prove desired results is
unethical.
PTS: 1 DIF: Cognitive Level: Analysis REF: p. 17
TOP: Nursing Process: Implementation
MSC: NCLEX Client Needs Category: Physiologic Integrity: Pharmacologic and Parenteral Therapies
6. A nurse is teaching nursing students about the use of nonproprietary names for drugs. The nurse
tells them which fact about nonproprietary names?
a. They are approved by the FDA and are
easy to remember.
b. They are assigned by the U.S. Adopted
Names Council.

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c. They clearly identify the drug’s
pharmacologic classification.
d. They imply the efficacy of the drug and
are less complex.
ANS: B
Nonproprietary, or generic, names are assigned by the U.S. Adopted Names Council, which
ensures that each drug has only one name. Trade names, or brand names, are approved by the
FDA and are easier to remember. Some nonproprietary names contain syllables that identify the
classification, although not all do. Drug names are not supposed to identify the use for the drug,
although some brand names do so.
PTS: 1 DIF: Cognitive Level: Comprehension REF: p. 18
TOP: Nursing Process: Diagnosis
MSC: NCLEX Client Needs Category: Physiologic Integrity: Reduction of Risk Potential

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