Building DNA Gizmo

Explore DNA structure and replication with this interactive activity. Learn key terms like double helix, nucleotide, and mutation. Understand how DNA copies itself by breaking base pair bonds.

Alice Edwards
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Name:Dale:10/14/21Student Exploration: Building DNADirections: Follow the instructions to go through the simulation. Respond to the questions andprompts in the orange boxes.Vocabulary:double helix. DNA. enzyme, mutation, nitrogenous base, nucleoside, nucleotide, replicationPrior Knowledge Questions (Do these BEFORE usingtheGizmo.)DNAis an incredible molecule that forms the basis of life on Earth.DNAmolecules contain instructions forbuilding every living organism on Earth, from the tiniesl bacterium to a massive blue whale. DNA also haslheability Ioreplicate,or make copies of itself. This allows living things to grow and reproduce.1.Lookalthe DNAmolecule shownat right. What does it look like?A figure 8 like shape and a double helixThis shape is called adoublehelix2.Based on this picture how do youthinka DNA molecule makes a copy of itself?(Hint: Lookatthe bottom two "rungs" oflheladder.)By breaking the bonds that connect the linkedbasesGizmo Warm-upThe fid/j/dingDNAGizmo allowsyoutoconstructaDNAmolecule and gothroughthe process ofDNAreplication Examinethe components thatmakeupa DNA molecule.1.What are the Iwo DNA components shown in the Gizmo?deoxyribose and a nitrogenous base.2.A nucleoside has two partsa pentagonal sugar (deoxyribose) and anitrogenous base (incolor). When a nucleoside is joined Io a phosphate, itis called a nucleotideHow many different nitrogenous bases do you see?Note: The names of these nitrogenous bases are adenine (red), cytosine (yellow), guanine (blue), andthymine (green).

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