Cell Division Gizmo-Exploring the Stages and Signi
Cells must grow during interphase to prepare for division, and DNA replicates so chromatids can separate to opposite poles, ensuring each daughter cell gets a full set of genetic information.
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g«l Gizmos
Name: Date: I
Studenlt Exploration: Cell Division
Directions: Follow the instructions to go through the simulation. Respond to the questions and
prompts in the orange boxes.
Vocabulary: cell division, centriole, centromere, chromatid, chromatin, chromosome, cytokinesis. DNA,
interphase, mitosis
Prior Knowledge Questions (Do these BEFORE using the Gizmo.)
1. Cells reproduce by splitting in half, a process called cell division. What do cells need to do between
divisions to make sure that they don't just get smaller and smaller?
They reed to go through interphase to make sure there is enough proteins and mass to
continue dividing
2. The genetic information of a cell is carried in its DNA (short for deoxyribonucleic acid). What do cells need
to do between divisions to make sure that a full set of DNA gets passed on to each daughter cell?
Chromatids need to each the opposite poles of the cell
Gizmo Warm-up
On the SIMULATION pane of the Cel! Division Gizmo, check that the Cycle
Length is set to 12 hours. Click Play { ►), observe until the maximum number of
cells is shown, and then click Pause ( " ).
1. Look at the cells. Do they all look the same? NO
2. Cells that are in the process of dividing are said to be in mitosis cr
cytokinesis. Cells that are net dividing are in interphase
Check the Magnify box and move the cursor over the cells.
A. Of the 100 cells shown, how many are in the process of dividing?
9
B. Select the BAR CHART tab, and turn on Show numerical values. How many cells are in the
interphase stage of their life cycle? 79
C. Based on these two observations, would you say that a cell spends most of its life cycle in
interphase or in mitosis/cytokinesis? Interphase
Name: Date: I
Studenlt Exploration: Cell Division
Directions: Follow the instructions to go through the simulation. Respond to the questions and
prompts in the orange boxes.
Vocabulary: cell division, centriole, centromere, chromatid, chromatin, chromosome, cytokinesis. DNA,
interphase, mitosis
Prior Knowledge Questions (Do these BEFORE using the Gizmo.)
1. Cells reproduce by splitting in half, a process called cell division. What do cells need to do between
divisions to make sure that they don't just get smaller and smaller?
They reed to go through interphase to make sure there is enough proteins and mass to
continue dividing
2. The genetic information of a cell is carried in its DNA (short for deoxyribonucleic acid). What do cells need
to do between divisions to make sure that a full set of DNA gets passed on to each daughter cell?
Chromatids need to each the opposite poles of the cell
Gizmo Warm-up
On the SIMULATION pane of the Cel! Division Gizmo, check that the Cycle
Length is set to 12 hours. Click Play { ►), observe until the maximum number of
cells is shown, and then click Pause ( " ).
1. Look at the cells. Do they all look the same? NO
2. Cells that are in the process of dividing are said to be in mitosis cr
cytokinesis. Cells that are net dividing are in interphase
Check the Magnify box and move the cursor over the cells.
A. Of the 100 cells shown, how many are in the process of dividing?
9
B. Select the BAR CHART tab, and turn on Show numerical values. How many cells are in the
interphase stage of their life cycle? 79
C. Based on these two observations, would you say that a cell spends most of its life cycle in
interphase or in mitosis/cytokinesis? Interphase
Get the Gizmo ready:
• Click Reset ( ° ).Activity A:
Phases of the cell
cycle
• Select the DESCRIPTION tab.
• Click on the right arrow once so that Interphase is
shown.
Question: What are the stages of the cell cycle?
1. Observe: Click Flay and hold the cursor over the cell. Observe the cell as it divides several times. (This
happens quickly!) What do you notice happening during this process?
The cell makes this light blue ball then splits in two white balls then another cell is
formed
2. Summarize: On the DESCRIPTION pane, read about each phase in the cell cycle. » In the spaces below,
sketch the cell in each phase and summarize what occurs ir your own words.
Phase Sketch Summary
Interphase
1nterph a s e has th ree stag es: G: . S. and Gs G ,. During S the
DNA contained in the cell chromatn is duplicated. G: Is
distinguish by the synthesis of the organelles
Prophase
This is the first stage of mitosis. In this stage the nucleolus
disappears and the chromat n condenses to form visible
chromosomes. Each chromosome has two chromatids
connected by a centromere. Outside the nucleus spindle
fibers begin to form between the centrioles which then make
their way to the opposite side of the cell. At the end of this
stage the nuclear membpane dissolves away.
Metaphase
Second stage of mitosis. The centromeres of each
chromosome are attached to spindle fibers. The spindle
fibers change their lergth and pull the chromosomes into a
line along the cell
Anaphase
Third stage of mitosis. The centromeres split and the sister
chromat ds are pulled to the opposite poles of the cell by the
spindle fibers. The stage ends once the chromatids reach the
poles and stop moving
Telophase Final stage of mitosis. During the final stage a nuclear
membr an= forms around each set of the daughter
chromosomes and the nucleus reappears in each nucleus.
Cytokinesis During cytokinesis the sides of the cell pinch inward dividing
the cytoplasm and forming two cells each containing a
complete copy of the parent cell dna
• Click Reset ( ° ).Activity A:
Phases of the cell
cycle
• Select the DESCRIPTION tab.
• Click on the right arrow once so that Interphase is
shown.
Question: What are the stages of the cell cycle?
1. Observe: Click Flay and hold the cursor over the cell. Observe the cell as it divides several times. (This
happens quickly!) What do you notice happening during this process?
The cell makes this light blue ball then splits in two white balls then another cell is
formed
2. Summarize: On the DESCRIPTION pane, read about each phase in the cell cycle. » In the spaces below,
sketch the cell in each phase and summarize what occurs ir your own words.
Phase Sketch Summary
Interphase
1nterph a s e has th ree stag es: G: . S. and Gs G ,. During S the
DNA contained in the cell chromatn is duplicated. G: Is
distinguish by the synthesis of the organelles
Prophase
This is the first stage of mitosis. In this stage the nucleolus
disappears and the chromat n condenses to form visible
chromosomes. Each chromosome has two chromatids
connected by a centromere. Outside the nucleus spindle
fibers begin to form between the centrioles which then make
their way to the opposite side of the cell. At the end of this
stage the nuclear membpane dissolves away.
Metaphase
Second stage of mitosis. The centromeres of each
chromosome are attached to spindle fibers. The spindle
fibers change their lergth and pull the chromosomes into a
line along the cell
Anaphase
Third stage of mitosis. The centromeres split and the sister
chromat ds are pulled to the opposite poles of the cell by the
spindle fibers. The stage ends once the chromatids reach the
poles and stop moving
Telophase Final stage of mitosis. During the final stage a nuclear
membr an= forms around each set of the daughter
chromosomes and the nucleus reappears in each nucleus.
Cytokinesis During cytokinesis the sides of the cell pinch inward dividing
the cytoplasm and forming two cells each containing a
complete copy of the parent cell dna
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