M6L2
Interactive cell‐cycle activity worksheet guiding students through Interphase, Prophase, Metaphase, Anaphase, Telophase, and Cytokinesis using a Gizmo simulation. Includes sketches, summaries, and analysis questions on chromosomes and centrioles.
Daniel Miller
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Name: quardell wilson Date:
Vocabulary: cell division, centriole, centromere, chromatid, chromatin, chromosome,
cytokinesis, DNA, interphase, mitosis
Prior Knowledge Questions (Do these BEFORE using the Gizmo.)
Cells reproduce by splitting in half, a process called cell division. What do cells need to do
between divisions to make sure that they don't just get smaller and smaller?
the cells need to grow in between divisions
The genetic information of a cell is carried in its DNA (short for deoxyribonucleic acid). What
do cells need to do between divisions to make sure that a full set of DNA gets passed on to
each daughter cell?
the cells need to duplicate its DNA
Gizmo Warm-up
O n the SIMULATION pane of the Celt Division Gizmo™, check that the Cycle Length is set to
1 2 hours. Click Play ( ) , observe until the maximum number of cells is shown, and then click
Pause ( ) .
Look at the cells. Do they all look the same? yes
Cells that are in the process of dividing are said to be in mitosis or cytokinesis . Cells that are
not dividing are in interphase.
Check the Magnify box and move the cursor over the cells.
Of the 100 cells shown, how many are in the process of
dividing?
1 9
Select the BAR CHART tab, and turn on Show numerical values.
How many cells are in the interphase stage of their life cycle? 8 1
Based on these two observations, would you say that a cell spends most of its
life cycle in interphase or in mitosis/cytokinesis?
interphase
Vocabulary: cell division, centriole, centromere, chromatid, chromatin, chromosome,
cytokinesis, DNA, interphase, mitosis
Prior Knowledge Questions (Do these BEFORE using the Gizmo.)
Cells reproduce by splitting in half, a process called cell division. What do cells need to do
between divisions to make sure that they don't just get smaller and smaller?
the cells need to grow in between divisions
The genetic information of a cell is carried in its DNA (short for deoxyribonucleic acid). What
do cells need to do between divisions to make sure that a full set of DNA gets passed on to
each daughter cell?
the cells need to duplicate its DNA
Gizmo Warm-up
O n the SIMULATION pane of the Celt Division Gizmo™, check that the Cycle Length is set to
1 2 hours. Click Play ( ) , observe until the maximum number of cells is shown, and then click
Pause ( ) .
Look at the cells. Do they all look the same? yes
Cells that are in the process of dividing are said to be in mitosis or cytokinesis . Cells that are
not dividing are in interphase.
Check the Magnify box and move the cursor over the cells.
Of the 100 cells shown, how many are in the process of
dividing?
1 9
Select the BAR CHART tab, and turn on Show numerical values.
How many cells are in the interphase stage of their life cycle? 8 1
Based on these two observations, would you say that a cell spends most of its
life cycle in interphase or in mitosis/cytokinesis?
interphase
Activity A:
Phases of the cell
cycle
Get the Gizmo ready
■ Click Reset ( ).
. Select the DESCRI PTION tab.
■ Click on the right arrow once so that
Interphase is shown.
® J
Question: What are the stages of the cell cycle?
Observe: Click Play and hold the cursor over the cell. Observe the cell as it divides several
times. (This happens quickly!)
What do you notice happening during this process?
I noticed that the nucleus disappeared and that chromatin little
x's
Summarize: On the DESCRIPTION pane, read about each phase in the cell cycle. In the
spaces below, sketch (or paste a drawing/picture of) the cell in each phase and summarize what
occurs in your own words.
Phase Sketch Summary
Interphase The cell is growing ano developing and the cell's DNA is duplicated. The cells
organelles are synthesized
Prophase line stage in which visible chromosomes are createo and the nucleolus
disappears
Metaphase
the centromeres attach themselves tD spindle fibers ana the spindle fibers
length changes which pulls the chromosome into a line by the miodle of the
cell
Anaphase centromeres split apart and the sister chromatins are pulled apart once the
chromatins reach the opposite poles they will stop moving
Telophase the nuclear membrane forms around the daughter chromosomes and the
nucleolus reappears in the nucleus
Cytokinesi
s
2 similar nuclei are formed and the cytoplasm is divided into the daughters
cells with a complete copy of the dna.
(Activity A continued on next page)
Phases of the cell
cycle
Get the Gizmo ready
■ Click Reset ( ).
. Select the DESCRI PTION tab.
■ Click on the right arrow once so that
Interphase is shown.
® J
Question: What are the stages of the cell cycle?
Observe: Click Play and hold the cursor over the cell. Observe the cell as it divides several
times. (This happens quickly!)
What do you notice happening during this process?
I noticed that the nucleus disappeared and that chromatin little
x's
Summarize: On the DESCRIPTION pane, read about each phase in the cell cycle. In the
spaces below, sketch (or paste a drawing/picture of) the cell in each phase and summarize what
occurs in your own words.
Phase Sketch Summary
Interphase The cell is growing ano developing and the cell's DNA is duplicated. The cells
organelles are synthesized
Prophase line stage in which visible chromosomes are createo and the nucleolus
disappears
Metaphase
the centromeres attach themselves tD spindle fibers ana the spindle fibers
length changes which pulls the chromosome into a line by the miodle of the
cell
Anaphase centromeres split apart and the sister chromatins are pulled apart once the
chromatins reach the opposite poles they will stop moving
Telophase the nuclear membrane forms around the daughter chromosomes and the
nucleolus reappears in the nucleus
Cytokinesi
s
2 similar nuclei are formed and the cytoplasm is divided into the daughters
cells with a complete copy of the dna.
(Activity A continued on next page)
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