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Solution Manual for Molecular Cell Biology , 8th Edition

Solve textbook problems faster with Solution Manual for Molecular Cell Biology, 8th Edition, a solutions guide designed to make your studies easier.

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1REVIEW THE CONCEPTS1.Less energy is required to form noncovalent bonds than covalent bonds, and thebonds that stick the gecko’s feet to the smooth surface need to be formed and brokenmany times as the animal moves. Since van der Waals interactions are so weak, theremust be many points of contact (a large surface area) yielding multiple van der Waalsinteractions between the septae and the smooth surface.2.a.These are likely to be hydrophilic amino acids, and in particular, negativelycharged amino acids (aspartate and glutamate), which would have an affinityfor K+via ionic bonds.b.Like the phospholipid bilayer itself, this portion of the protein is likely to beamphipathic, with hydrophobic amino acids in contact with the fatty acyl chainsand hydrophilic amino acids in contact with the hydrophilic heads.c, d.Since both the cytosol and extracellular space are aqueous environments,hydrophilic amino acids would contact these fluids.3.At pH = 7.0, the net charge is –1 because of the negative charge on the carboxyl resi-due of glutamate (E). After phosphorylation by a tyrosine kinase, two additional nega-tive charges (because of attachment of phosphate residues to tyrosines (Y)) would beadded. Thus, the net charge would be –3. The most likely source of phosphate is ATPsince the attachment of inorganic phosphate (Pi) to tyrosine is energetically highlyunfavorable, but when coupled to the hydrolysis of the high-energy phosphoan-hydride bond of ATP, the overall reaction is energetically favorable.2CHEMICAL FOUNDATIONS

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Subject
Biology
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Molecular Cell Biology by Harvey Lo...

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