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Histology - Cardiac Development Part 1

Anatomy and Physiology25 CardsCreated about 1 month ago

This flashcard deck covers key concepts in cardiac development, focusing on the anatomical and physiological changes during embryonic heart formation.

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Inflow chambers (RA/LA) located

posteriorly & to the right.
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Key Terms

Term
Definition
Inflow chambers (RA/LA) located
posteriorly & to the right.
Apex of heart to right side due to abnormal cardiac looping. Can occur alone or with Situs Inversus.
Dextrocardia
Week 8
Formation of Atrioventricular Valves (AV) Completed
Truncus arteriosus (TA) gives rise to
Ascending aorta and pulmonary trunk
patent foramen ovale
caused by excessive resorption of septum primum and/or secundum.
Sinus venosus (R sinus horn) becomes…
Smooth part of right atrium
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Histology - Cardiac Development Part 1
TermDefinition
Inflow chambers (RA/LA) located
posteriorly & to the right.
Apex of heart to right side due to abnormal cardiac looping. Can occur alone or with Situs Inversus.
Dextrocardia
Week 8
Formation of Atrioventricular Valves (AV) Completed
Truncus arteriosus (TA) gives rise to
Ascending aorta and pulmonary trunk
patent foramen ovale
caused by excessive resorption of septum primum and/or secundum.
Sinus venosus (R sinus horn) becomes…
Smooth part of right atrium
Chordae tendinae and Papillary muscles originate from…
hollowed out Ventricular Wall
4th aortic arch becomes
on left, aortic arch; on right, proximal part of right subclavian artery. (4 limbs; systemic)
Outgrowths of conotruncal walls that fuse to form Aorticopulmonary septum. Originate from neural crest and endothelial cells (E-M transformation)
Conotruncal Cushions (CTCs)
A transcription factor from the primitive node that is swept to the left side of the embryo. It induces lateral plate mesoderm to form left-side structures by promoting expression of Pitx2.
Nodal
Bulbus cordis becomes
ight ventricle (trabeculated portion)
Right horn of SV gives rise to
Smooth part of right atrium
Completed by end of Week 4. Results in adult heart orientation, and differentiation of heart tube regions (precursors of adult heart structures).
Cardiac looping
“Up-growth” of muscular wall of primitive ventricle toward the fused ECs. Tissue from the anterior endocardial cushion proliferates, growing superiorly to meet the downward growing conotruncal septum.
Formation of Interventricular septum
Formed from four endocardial cushions (thickenings) at the near end of the truncus arteriosus.
semilunar valve formation
primitive ventircle gives rise to
Trabeculated left and right ventricles
Patent foramen ovale (PFO) 2. Other atrial septal defects (ASDs)
Anomalies of Interatrial Septum formation
Left horn of sinus venosus (SV) gives rise to
Coronary sinus
Right common cardinal vein and right anterior cardinal vein gives rise to
CVS
developmentally formed from neural crest, specifically the cardiac neural crest, and actively separates the aorta and pulmonary arteries and fuses with the interventricular septum within the heart during development.
aorticopulmonary (spiral, conotruncal) septum
Migrate to outflow tract to stimulate the SHF that contributes to cardiac looping, contribute to cushion tissue for hart partition, and contribute to semilunar valve formation.
Neural crest cells associated with pharyngeal arches 3,4,6
3rd aortic arch becomes
common Carotid artery and proximal part of internal carotid artery. (C is 3rd letter of alphabet)
EARLY WEEK 4. Cells migrate from the tissues on the surface of the septum transversum & sinus horns near the inflow vessels to form the epicardium. HEART BEGINS TO BEAT!
Heart (endocardial) tube fusion
Outflow (AA & PT) located
Anteriorly
6th aortic arch becomes
proximal part of pulmonary arteries and (on left only) ductus arteriosus.