Back to AI Flashcard MakerAnatomy and Physiology /Histology Fetal Development and Complications - Reverse Part 3
Histology Fetal Development and Complications - Reverse Part 3
This deck covers key concepts in fetal development and associated complications, focusing on histological aspects and genetic mutations.
forms urogenital system
Intermediate mesoderm
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Key Terms
Term
Definition
forms urogenital system
Intermediate mesoderm
forms connective tissue of body wall and limbs
parietal layer of lateral plate mesoderm
GI/respiratory organs exxcept epithelial lining
visceral layer of lateral plate mesoderm
somites differentiate (wk 4), myotome differentiation (wk 5), resegmentation (wk 5), organogenesis
Weeks 4-8
chondrification centers for vertebral column develop
week 6
primary ossification centers for vertebral column develop
week 7
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| Term | Definition |
|---|---|
forms urogenital system | Intermediate mesoderm |
forms connective tissue of body wall and limbs | parietal layer of lateral plate mesoderm |
GI/respiratory organs exxcept epithelial lining | visceral layer of lateral plate mesoderm |
somites differentiate (wk 4), myotome differentiation (wk 5), resegmentation (wk 5), organogenesis | Weeks 4-8 |
chondrification centers for vertebral column develop | week 6 |
primary ossification centers for vertebral column develop | week 7 |
ribs form (sclerotome), tail regresses, limbs rotate/enlongate, digits and face develop, | week 8 |
produces floating ribs | hox9 |
prevents rib formation | hox 10 |
from parietal layer of lateral plate mesoderm | sternum formation |
sacralization of vertebrae | Hox11 |
rostral neuropore doesn't close | Anencephaly |
causal neuropore doesn't close | spina bifida |
malformed pelvis, underdeveloped lower limbs, 250X more in pregestational diabetics | Caudal dysgenesis |
form of CD, mermaid syndrome | Sirenomelia |
Loss of function: ribcages with all ribs attacted to sternum | Mutation of Hox9 |
Loss of function: lumbar and sacral vertebrae with ribs. Gain of function: Thoracic vertebrae without ribs | Mutation of Hox10 |
LoF: Sacral vertevrae that donot fuse. GoF: vertebrae at various levels fusing | Mutation of Hox 11 |
fracture of pars interarticularis | Spondylolysis |
Hox11 gain of function mutation at L5 | Sacralization of L5 vertebra |
bone ossification centers (wk 12), ext genetalia visible (wk 12), swallowing and urine formation (wk 10), respiratory movements (wk 15) | Weeks 9+ (fetal period) |
weeks 24 - 28 | Sound and light recognition |